Professor Emeritus
Psychiatry
+1 415 476-7861
Publications
Gene Targeting Models of Epilepsy: Technical and Analytical Considerations.
Neuropharmacology Methods in Epilepsy Research
Mice Lacking Serotonin 2C Receptors Have increased Affective Responses to Aversive Stimuli.
PloS one
Elucidation of The Behavioral Program and Neuronal Network Encoded by Dorsal Raphe Serotonergic Neurons.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Gai/o-coupled receptor signaling restricts pancreatic ß-cell expansion.
Proceedings of the National Academy of Sciences of the United States of America
Axonal control of the adult neural stem cell niche.
Cell stem cell
Serotonin and the regulation of mammalian energy balance.
Frontiers in neuroscience
Impact of serotonin (5-HT)2C receptors on executive control processes.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
The Role of 5-HT2C Receptors in the Pathophysiology and Treatment of Depression.
5-HT2C Receptors in the Pathophysiology of CNS Disease
Precise pattern of recombination in serotonergic and hypothalamic neurons in a Pdx1-cre transgenic mouse line.
Journal of biomedical science
CREB mediates brain serotonin regulation of bone mass through its expression in ventromedial hypothalamic neurons.
Genes & development
Serotonin regulates pancreatic beta cell mass during pregnancy.
Nature medicine
Serotonin activates murine alveolar macrophages through 5-HT2C receptors.
American journal of physiology. Lung cellular and molecular physiology
Reduced conditioned fear response in mice that lack Dlx1 and show subtype-specific loss of interneurons.
Journal of neurodevelopmental disorders
Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Rodent Behavior: Approaches.
Encyclopedia of Neuroscience
A robust automated system elucidates mouse home cage behavioral structure.
Proceedings of the National Academy of Sciences of the United States of America
It is time to take a stand for medical research and against terrorism targeting medical scientists.
Biological psychiatry
Relevance of animal models to human eating disorders and obesity.
Psychopharmacology
Expression level of 5-HT1A receptor alters firing rate and concentration-dependency in YFP-labeled 5-HT dorsal raphe neurons.
The FASEB Journal
5-HT(1A) Receptor Null Mutant Mice Responding Under a Differential-Reinforcement-of-Low-Rate 72-Second Schedule of Reinforcement.
The open neuropsychopharmacology journal
A novel method for automatic quantification of psychostimulant-evoked route-tracing stereotypy: application to Mus musculus.
Psychopharmacology
Synergistic impairment of glucose homeostasis in ob/ob mice lacking functional serotonin 2C receptors.
Endocrinology
Serotonin and the orchestration of energy balance.
Cell metabolism
Serotonin activates the hypothalamic-pituitary-adrenal axis via serotonin 2C receptor stimulation.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons.
Nature neuroscience
Alpha1-adrenergic receptors prevent a maladaptive cardiac response to pressure overload.
The Journal of clinical investigation
A null mutation of the serotonin 6 receptor alters acute responses to ethanol.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Molecular determinants in the second intracellular loop of the 5-hydroxytryptamine-1A receptor for G-protein coupling.
Molecular pharmacology
Serotonin System Gene Knockouts.
The Serotonin Receptors
Inactivation of 5-HT(2C) receptors potentiates consequences of serotonin reuptake blockade.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Neurobehavioral assessment in the information age.
Nature neuroscience
Contributions of 5-HT(2C) receptors to multiple actions of central serotonin systems.
European journal of pharmacology
Mouse genetic approaches to feeding regulation: serotonin 5-HT2C receptor mutant mice.
CNS spectrums
Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor.
Nature neuroscience
Central serotonin and melanocortin pathways regulating energy homeostasis.
Annals of the New York Academy of Sciences
The genes and brains of mice and men.
The American journal of psychiatry
Enhanced locomotor, reinforcing, and neurochemical effects of cocaine in serotonin 5-hydroxytryptamine 2C receptor mutant mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Sleep and sleep homeostasis in mice lacking the 5-HT2c receptor.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Activation of central melanocortin pathways by fenfluramine.
Science (New York, N.Y.)
Altered gene expressions involved in energy expenditure in 5-HT(2C) receptor mutant mice.
Biochemical and biophysical research communications
Serotonin 5- HT (2C) receptor knockout mice: autoradiographic analysis of multiple serotonin receptors.
Journal of neuroscience research
FOOD INTAKE IN THE GENETICALLY ALTERED MOUSE.
Behavioural Pharmacology
Knockout Corner: Neurobehavioural consequences of a serotonin 5-HT(2C) receptor gene mutation.
The international journal of neuropsychopharmacology
NEUROBEHAVIORAL ANALYSIS OF SEROTONIN RECEPTOR MUTANT MICE.
Behavioural Pharmacology
NEUROBEHAVIORAL ANALYSIS OF SEROTONIN RECEPTOR MUTANT MICE.
Behavioural Pharmacology
NEUROBEHAVIORAL ANALYSIS OF SEROTONIN RECEPTOR MUTANT MICE.
Behavioural Pharmacology
Gene Targeting Models of Epilepsy.
Neuropharmacology Methods in Epilepsy Research
Gene targeting approaches to analyse neurotransmitter receptor function.
Seminars in Neuroscience
Methodological Considerations in the Utilization of In Situ Hybridization.
In Situ Hybridization in Neurobiology