Professional Research
Biochemistry and Biophysics
+1 415 476-7284
Dr. Jue Lin is a molecular biologist and Director of the Telomere Biology Core Lab in Dr. Elizabeth Blackburn’s laboratory. Her research focuses on telomere maintenance in health and disease, using a variety of approaches, including in vitro and ex vivo cell culture models, animal models, as well as clinical studies.
Publications
Rare SV2C coding variants in Parkinson's disease risk.
Journal of Parkinson's disease
Evaluating Mild Cognitive Dysfunction in Patients with Parkinson's Disease in Clinical Practice in Taiwan.
Scientific reports
Telomere length measurement by qPCR - Summary of critical factors and recommendations for assay design.
Psychoneuroendocrinology
In vitro proinflammatory gene expression predicts in vivo telomere shortening: A preliminary study.
Psychoneuroendocrinology
Variability of presynaptic nigrostriatal dopaminergic function and clinical heterogeneity in a dopa-responsive dystonia family with GCH-1 gene mutation.
Journal of neurology
Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study.
Neurobiology of aging
PDD-5S: A useful screening tool for Parkinson's disease dementia.
Parkinsonism & related disorders
TREM2 R47H variant and risk of essential tremor: a cross-sectional international multicenter study.
Parkinsonism & related disorders
Spinocerebellar ataxia 35: novel mutations in TGM6 with clinical and genetic characterization.
Neurology
Comparison of activities of daily living impairments in Parkinson's disease patients as defined by the Pill Questionnaire and assessments by neurologists.
Journal of neurology, neurosurgery, and psychiatry
Reversible oro-lingual dyskinesia related to lithium intoxication.
Acta neurologica Taiwanica
A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants.
Journal of medical genetics
Familial paroxysmal nonkinesigenic dyskinesia: clinical and genetic analysis of a Taiwanese family.
Journal of the neurological sciences
Telomeres and lifestyle factors: roles in cellular aging.
Mutation research
Generalized chorea in the syndrome of acute bilateral basal ganglia lesions in patients with diabetic uremia.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan.
The New England journal of medicine
High frequency of multiexonic deletion of the GCH1 gene in a Taiwanese cohort of dopa-response dystonia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease.
Neurobiology of aging
Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance.
Journal of immunological methods
Safety/Tolerability and efficacy of rivastigmine in taiwanese patients with Alzheimer's disease: a prospective post-marketing surveillance study.
Clinical drug investigation
5,10-methylenetetrahydrofolate reductase C677T gene polymorphism can influence age at onset of Parkinson's disease.
Acta neurologica Taiwanica
Genetic polymorphism of the angiotensin converting enzyme and L-dopa-induced adverse effects in Parkinson's disease.
Journal of the neurological sciences
Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions.
Pharmacogenetics and genomics
Homozygous deletion genotype of angiotensin converting enzyme confers protection against migraine in man.
Acta neurologica Taiwanica
Lumbar zygapophyseal joint injections in patients with chronic lower back pain.
Journal of the Chinese Medical Association : JCMA
Camptocormia in Parkinson's disease.
Acta neurologica Taiwanica
Improvement of generalised dystonia by olanzapine treatment.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
The homozygote 10-copy genotype of variable number tandem repeat dopamine transporter gene may confer protection against Parkinson's disease for male, but not to female patients.
Journal of the neurological sciences
Association between genetic polymorphism of angiotensin-converting enzyme gene and Parkinson's disease.
Journal of the neurological sciences