Ronald Krauss, MD

Professor in Residence
Pediatrics

Dr. Krauss' research program focuses on plasma lipoprotein metabolism and related traits that influence risk for coronary artery disease. His laboratory developed and applied methodology that led to the discovery of a common genetically-influenced atherogenic lipoprotein phenotype that underlies cardiovascular disease risk in patients with obesity, type 2 diabetes, and metabolic syndrome. A major current research emphasis has been the identification of genetic determinants of the wide range of inter-individual variability in phenotypic and clinical response to statin treatment. Multiple statin-treated population samples are being examined to test the reproducibility and generalizability of findings derived from both candidate gene and genome-wide searches for SNP associations with markers of statin efficacy as well as muscle toxicity. Functional significance of genetic findings is being evaluated in appropriate human cellular and animal models, with the goal of connecting genotypes to clinically relevant determinants of cardiovascular disease risk.

Publications: 

Competing paradigms of obesity pathogenesis: energy balance versus carbohydrate-insulin models.

European journal of clinical nutrition

Ludwig DS, Apovian CM, Aronne LJ, Astrup A, Cantley LC, Ebbeling CB, Heymsfield SB, Johnson JD, King JC, Krauss RM, Taubes G, Volek JS, Westman EC, Willett WC, Yancy WS, Friedman MI

Polygenic risk score and statin relative risk reduction for primary prevention of myocardial infarction in a real-world population.

Clinical pharmacology and therapeutics

Oni-Orisan A, Haldar T, Cayabyab MAS, Ranatunga DK, Hoffmann TJ, Iribarren C, Krauss RM, Risch N

Undifferentiated Induced Pluripotent Stem Cells as a Genetic Model for Nonalcoholic Fatty Liver Disease.

Cellular and molecular gastroenterology and hepatology

Muñoz A, Theusch E, Kuang YL, Nalula G, Peaslee C, Dorlhiac G, Landry MP, Streets A, Krauss RM, Iribarren C, Mattis AN, Medina MW

Modest effect of statins on fasting glucose in a longitudinal electronic health record based cohort.

Cardiovascular diabetology

Haldar T, Oni-Orisan A, Hoffmann TJ, Schaefer C, Iribarren C, Krauss RM, Medina MW, Risch N

Lipoprotein subfractions and subclinical vascular health in middle aged women: does menopause status matter?

Menopause (New York, N.Y.)

Qi M, Chen X, Krauss RM, Matthews K, Janssen I, Brooks MM, McConnell D, Crawford SL, El Khoudary SR

Remnant lipoprotein particles and cardiovascular disease risk.

Best practice & research. Clinical endocrinology & metabolism

Krauss RM, King SM

A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation.

Nature genetics

Vujkovic M, Ramdas S, Lorenz KM, Guo X, Darlay R, Cordell HJ, He J, Gindin Y, Chung C, Myers RP, Schneider CV, Park J, Lee KM, Serper M, Carr RM, Kaplan DE, Haas ME, MacLean MT, Witschey WR, Zhu X, Tcheandjieu C, Kember RL, Kranzler HR, Verma A, Giri A, Klarin DM, Sun YV, Huang J, Huffman JE, Townsend Creasy K, Hand NJ, Liu CT, Long MT, Yao J, Budoff M, Tan J, Li X, Lin HJ, Chen YI, Taylor KD, Chang RK, Krauss RM, Vilarinho S, Brancale J, Nielsen JB, Locke AE, Jones MB, Verweij N, Baras A, Reddy KR, Neuschwander-Tetri BA, Schwimmer JB, Sanyal AJ, Chalasani N, Ryan KA, Mitchell BD, Gill D, Wells AD, Manduchi E, Saiman Y, Mahmud N, Miller DR, Reaven PD, Phillips LS, Muralidhar S, DuVall SL, Lee JS, Assimes TL, Pyarajan S, Cho K, Edwards TL, Damrauer SM, Wilson PW, Gaziano JM, O'Donnell CJ, Khera AV, Grant SFA, Brown CD, Tsao PS, Saleheen D, Lotta LA, Bastarache L, Anstee QM, Daly AK, Meigs JB, Rotter JI, Lynch JA, Regeneron Genetics Center, Geisinger-Regeneron DiscovEHR Collaboration, EPoS Consortium, VA Million Veteran Program, Rader DJ, Voight BF, Chang KM

The small HDL particle hypothesis of Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Martinez AE, Weissberger G, Kuklenyik Z, He X, Meuret C, Parekh T, Rees JC, Parks BA, Gardner MS, King SM, Collier TS, Harrington MG, Sweeney MD, Wang X, Zlokovic BV, Joe E, Nation DA, Schneider LS, Chui HC, Barr JR, Han SD, Krauss RM, Yassine HN

Meta-GWAS of PCSK9 levels detects two novel loci at APOB and TM6SF2.

Human molecular genetics

Pott J, Gadin J, Theusch E, Kleber ME, Delgado GE, Kirsten H, Hauck SM, Burkhardt R, Scharnagl H, Krauss RM, Loeffler M, März W, Thiery J, Silveira A, Vant Hooft FM, Scholz M

The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and Statin-Associated Musculoskeletal Symptoms.

Clinical pharmacology and therapeutics

Cooper-DeHoff RM, Niemi M, Ramsey LB, Luzum JA, Tarkiainen EK, Straka RJ, Gong L, Tuteja S, Wilke RA, Wadelius M, Larson EA, Roden DM, Klein TE, Yee SW, Krauss RM, Turner RM, Palaniappan L, Gaedigk A, Giacomini KM, Caudle KE, Voora D

Reply to A Drewnowski et al, O Devinsky, D A Booth and E L Gibson, and D J Millward.

The American journal of clinical nutrition

Ludwig DS, Aronne LJ, Astrup A, de Cabo R, Cantley LC, Friedman MI, Heymsfield SB, Johnson JD, King JC, Krauss RM, Lieberman DE, Taubes G, Volek JS, Westman EC, Willett WC, Yancy WS, Ebbeling CB

A gene-diet interaction controlling relative intake of dietary carbohydrates and fats.

Molecular metabolism

Nelson NG, Wu L, Maier MT, Lam D, Cheang R, Alba D, Huang A, Neumann DA, Hill T, Vagena E, Barsh GS, Medina MW, Krauss RM, Koliwad SK, Xu AW

The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction.

Frontiers in pharmacology

Trompet S, Postmus I, Warren HR, Noordam R, Smit RAJ, Theusch E, Li X, Arsenault B, Chasman DI, Hitman GA, Munroe PB, Rotter JI, Psaty BM, Caulfield MJ, Krauss RM, Cupples AL, Jukema WJ

The microbial gbu gene cluster links cardiovascular disease risk associated with red meat consumption to microbiota L-carnitine catabolism.

Nature microbiology

Buffa JA, Romano KA, Copeland MF, Cody DB, Zhu W, Galvez R, Fu X, Ward K, Ferrell M, Dai HJ, Skye S, Hu P, Li L, Parlov M, McMillan A, Wei X, Nemet I, Koeth RA, Li XS, Wang Z, Sangwan N, Hajjar AM, Dwidar M, Weeks TL, Bergeron N, Krauss RM, Tang WHW, Rey FE, DiDonato JA, Gogonea V, Gerberick GF, Garcia-Garcia JC, Hazen SL

The power of genetic diversity in genome-wide association studies of lipids.

Nature

Graham SE, Clarke SL, Wu KH, Kanoni S, Zajac GJM, Ramdas S, Surakka I, Ntalla I, Vedantam S, Winkler TW, Locke AE, Marouli E, Hwang MY, Han S, Narita A, Choudhury A, Bentley AR, Ekoru K, Verma A, Trivedi B, Martin HC, Hunt KA, Hui Q, Klarin D, Zhu X, Thorleifsson G, Helgadottir A, Gudbjartsson DF, Holm H, Olafsson I, Akiyama M, Sakaue S, Terao C, Kanai M, Zhou W, Brumpton BM, Rasheed H, Ruotsalainen SE, Havulinna AS, Veturi Y, Feng Q, Rosenthal EA, Lingren T, Pacheco JA, Pendergrass SA, Haessler J, Giulianini F, Bradford Y, Miller JE, Campbell A, Lin K, Millwood IY, Hindy G, Rasheed A, Faul JD, Zhao W, Weir DR, Turman C, Huang H, Graff M, Mahajan A, Brown MR, Zhang W, Yu K, Schmidt EM, Pandit A, Gustafsson S, Yin X, Luan J, Zhao JH, Matsuda F, Jang HM, Yoon K, Medina-Gomez C, Pitsillides A, Hottenga JJ, Willemsen G, Wood AR, Ji Y, Gao Z, Haworth S, Mitchell RE, Chai JF, Aadahl M, Yao J, Manichaikul A, Warren HR, Ramirez J, Bork-Jensen J, Kårhus LL, Goel A, Sabater-Lleal M, Noordam R, Sidore C, Fiorillo E, McDaid AF, Marques-Vidal P, Wielscher M, Trompet S, Sattar N, Møllehave LT, Thuesen BH, Munz M, Zeng L, Huang J, Yang B, Poveda A, Kurbasic A, Lamina C, Forer L, Scholz M, Galesloot TE, Bradfield JP, Daw EW, Zmuda JM, Mitchell JS, Fuchsberger C, Christensen H, Brody JA, Feitosa MF, Wojczynski MK, Preuss M, Mangino M, Christofidou P, Verweij N, Benjamins JW, Engmann J, Kember RL, Slieker RC, Lo KS, Zilhao NR, Le P, Kleber ME, Delgado GE, Huo S, Ikeda DD, Iha H, Yang J, Liu J, Leonard HL, Marten J, Schmidt B, Arendt M, Smyth LJ, Cañadas-Garre M, Wang C, Nakatochi M, Wong A, Hutri-Kähönen N, Sim X, Xia R, Huerta-Chagoya A, Fernandez-Lopez JC, Lyssenko V, Ahmed M, Jackson AU, Irvin MR, Oldmeadow C, Kim HN, Ryu S, Timmers PRHJ, Arbeeva L, Dorajoo R, Lange LA, Chai X, Prasad G, Lorés-Motta L, Pauper M, Long J, Li X, Theusch E, Takeuchi F, Spracklen CN, Loukola A, Bollepalli S, Warner SC, Wang YX, Wei WB, Nutile T, Ruggiero D, Sung YJ, Hung YJ, Chen S, Liu F, Yang J, Kentistou KA, Gorski M, Brumat M, Meidtner K, Bielak LF, Smith JA, Hebbar P, Farmaki AE, Hofer E, Lin M, Xue C, Zhang J, Concas MP, Vaccargiu S, van der Most PJ, Pitkänen N, Cade BE, Lee J, van der Laan SW, Chitrala KN, Weiss S, Zimmermann ME, Lee JY, Choi HS, Nethander M, Freitag-Wolf S, Southam L, Rayner NW, Wang CA, Lin SY, Wang JS, Couture C, Lyytikäinen LP, Nikus K, Cuellar-Partida G, Vestergaard H, Hildalgo B, Giannakopoulou O, Cai Q, Obura MO, van Setten J, Li X, Schwander K, Terzikhan N, Shin JH, Jackson RD, Reiner AP, Martin LW, Chen Z, Li L, Highland HM, Young KL, Kawaguchi T, Thiery J, Bis JC, Nadkarni GN, Launer LJ, Li H, Nalls MA, Raitakari OT, Ichihara S, Wild SH, Nelson CP, Campbell H, Jäger S, Nabika T, Al-Mulla F, Niinikoski H, Braund PS, Kolcic I, Kovacs P, Giardoglou T, Katsuya T, Bhatti KF, de Kleijn D, de Borst GJ, Kim EK, Adams HHH, Ikram MA, Zhu X, Asselbergs FW, Kraaijeveld AO, Beulens JWJ, Shu XO, Rallidis LS, Pedersen O, Hansen T, Mitchell P, Hewitt AW, Kähönen M, Pérusse L, Bouchard C, Tönjes A, Chen YI, Pennell CE, Mori TA, Lieb W, Franke A, Ohlsson C, Mellström D, Cho YS, Lee H, Yuan JM, Koh WP, Rhee SY, Woo JT, Heid IM, Stark KJ, Völzke H, Homuth G, Evans MK, Zonderman AB, Polasek O, Pasterkamp G, Hoefer IE, Redline S, Pahkala K, Oldehinkel AJ, Snieder H, Biino G, Schmidt R, Schmidt H, Chen YE, Bandinelli S, Dedoussis G, Thanaraj TA, Kardia SLR, Kato N, Schulze MB, Girotto G, Jung B, Böger CA, Joshi PK, Bennett DA, De Jager PL, Lu X, Mamakou V, Brown M, Caulfield MJ, Munroe PB, Guo X, Ciullo M, Jonas JB, Samani NJ, Kaprio J, Pajukanta P, Adair LS, Bechayda SA, de Silva HJ, Wickremasinghe AR, Krauss RM, Wu JY, Zheng W, den Hollander AI, Bharadwaj D, Correa A, Wilson JG, Lind L, Heng CK, Nelson AE, Golightly YM, Wilson JF, Penninx B, Kim HL, Attia J, Scott RJ, Rao DC, Arnett DK, Walker M, Koistinen HA, Chandak GR, Yajnik CS, Mercader JM, Tusié-Luna T, Aguilar-Salinas CA, Villalpando CG, Orozco L, Fornage M, Tai ES, van Dam RM, et al

The carbohydrate-insulin model: a physiological perspective on the obesity pandemic.

The American journal of clinical nutrition

Ludwig DS, Aronne LJ, Astrup A, de Cabo R, Cantley LC, Friedman MI, Heymsfield SB, Johnson JD, King JC, Krauss RM, Lieberman DE, Taubes G, Volek JS, Westman EC, Willett WC, Yancy WS, Ebbeling CB

Fecal Microbiome Composition Does Not Predict Diet-Induced TMAO Production in Healthy Adults.

Journal of the American Heart Association

Ferrell M, Bazeley P, Wang Z, Levison BS, Li XS, Jia X, Krauss RM, Knight R, Lusis AJ, Garcia-Garcia JC, Hazen SL, Tang WHW

Alternative Dietary Patterns for Americans: Low-Carbohydrate Diets.

Nutrients

Volek JS, Phinney SD, Krauss RM, Johnson RJ, Saslow LR, Gower B, Yancy WS, King JC, Hecht FM, Teicholz N, Bistrian BR, Hamdy O

Dietary Saturated Fats and Health: Are the U.S. Guidelines Evidence-Based?

Nutrients

Astrup A, Teicholz N, Magkos F, Bier DM, Brenna JT, King JC, Mente A, Ordovas JM, Volek JS, Yusuf S, Krauss RM

Effect of SLCO1B1 T521C on Statin-related Myotoxicity with Use of Lovastatin and Atorvastatin.

Clinical pharmacology and therapeutics

Lu B, Sun L, Seraydarian M, Hoffmann TJ, Medina MW, Iribarren C, Krauss RM, Risch N, Oni-Orisan A

A unified framework identifies new links between plasma lipids and diseases from electronic medical records across large-scale cohorts.

Nature genetics

Veturi Y, Lucas A, Bradford Y, Hui D, Dudek S, Theusch E, Verma A, Miller JE, Kullo I, Hakonarson H, Sleiman P, Schaid D, Stein CM, Edwards DRV, Feng Q, Wei WQ, Medina MW, Krauss RM, Hoffmann TJ, Risch N, Voight BF, Rader DJ, Ritchie MD

Effects of Palm Stearin versus Butter in the Context of Low-Carbohydrate/High-Fat and High-Carbohydrate/Low-Fat Diets on Circulating Lipids in a Controlled Feeding Study in Healthy Humans.

Nutrients

Hyde PN, Sapper TN, LaFountain RA, Kackley ML, Buga A, Fell B, Crabtree CD, Phinney SD, Miller VJ, King SM, Krauss RM, Kraemer WJ, Volek JS

Efficacy of AAV9-mediated SGPL1 gene transfer in a mouse model of S1P lyase insufficiency syndrome.

JCI insight

Zhao P, Tassew GB, Lee JY, Oskouian B, Muñoz DP, Hodgin JB, Watson GL, Tang F, Wang JY, Luo J, Yang Y, King SM, Krauss RM, Keller N, Saba JD

Correction to: Impact of a 2-year trial of nutritional ketosis on indices of cardiovascular disease risk in patients with type 2 diabetes.

Cardiovascular diabetology

Athinarayanan SJ, Hallberg SJ, McKenzie AL, Lechner K, King S, McCarter JP, Volek JS, Phinney SD, Krauss RM

Impact of a 2-year trial of nutritional ketosis on indices of cardiovascular disease risk in patients with type 2 diabetes.

Cardiovascular diabetology

Athinarayanan SJ, Hallberg SJ, McKenzie AL, Lechner K, King S, McCarter JP, Volek JS, Phinney SD, Krauss RM

Randomized nutrient bar supplementation improves exercise-associated changes in plasma metabolome in adolescents and adult family members at cardiometabolic risk.

PloS one

Mietus-Snyder M, Narayanan N, Krauss RM, Laine-Graves K, McCann JC, Shigenaga MK, McHugh TH, Ames BN, Suh JH

Consensus Statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the Management of Dyslipidemia and Prevention of Cardiovascular Disease Algorithm - 2020 Executive Summary.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists

Handelsman Y, Jellinger PS, Guerin CK, Bloomgarden ZT, Brinton EA, Budoff MJ, Davidson MH, Einhorn D, Fazio S, Fonseca VA, Garber AJ, Grunberger G, Krauss RM, Mechanick JI, Rosenblit PD, Smith DA, Wyne KL

Genetic variants modulate gene expression statin response in human lymphoblastoid cell lines.

BMC genomics

Theusch E, Chen YI, Rotter JI, Krauss RM, Medina MW

Public health guidelines should recommend reducing saturated fat consumption as much as possible: NO.

The American journal of clinical nutrition

Krauss RM, Kris-Etherton PM

Public health guidelines should recommend reducing saturated fat consumption as much as possible: YES.

The American journal of clinical nutrition

Kris-Etherton PM, Krauss RM

Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel.

European heart journal

Borén J, Chapman MJ, Krauss RM, Packard CJ, Bentzon JF, Binder CJ, Daemen MJ, Demer LL, Hegele RA, Nicholls SJ, Nordestgaard BG, Watts GF, Bruckert E, Fazio S, Ference BA, Graham I, Horton JD, Landmesser U, Laufs U, Masana L, Pasterkamp G, Raal FJ, Ray KK, Schunkert H, Taskinen MR, van de Sluis B, Wiklund O, Tokgozoglu L, Catapano AL, Ginsberg HN

Saturated Fats and Health: A Reassessment and Proposal for Food-based Recommendations: JACC State-of -the-Art Review.

Journal of the American College of Cardiology

Astrup A, Magkos F, Bier DM, Brenna JT, de Oliveira Otto MC, Hill JO, King JC, Mente A, Ordovas JM, Volek JS, Yusuf S, Krauss RM

Lipoprotein Particle Predictors of Arterial Stiffness after 17 Years of Follow Up: The Malmö Diet and Cancer Study.

International journal of vascular medicine

Hartz J, Krauss RM, Göttsater M, Melander O, Nilsson P, Mietus-Snyder M

Phosphatidylinositol-(4,5)-Bisphosphate Regulates Plasma Cholesterol Through LDL (Low-Density Lipoprotein) Receptor Lysosomal Degradation.

Arteriosclerosis, thrombosis, and vascular biology

Qin Y, Ting F, Kim MJ, Strelnikov J, Harmon J, Gao F, Dose A, Teng BB, Alipour MA, Yao Z, Crooke R, Krauss RM, Medina MW

High-Risk Atherosclerosis and Metabolic Phenotype: The Roles of Ectopic Adiposity, Atherogenic Dyslipidemia, and Inflammation.

Metabolic syndrome and related disorders

Lechner K, McKenzie AL, Kränkel N, Von Schacky C, Worm N, Nixdorff U, Lechner B, Scherr J, Weingärtner O, Krauss RM

Comparison of nonfasting and fasting lipoprotein subfractions and size in 15,397 apparently healthy individuals: An analysis from the VITamin D and OmegA-3 TriaL.

Journal of clinical lipidology

Farukhi ZM, Demler OV, Caulfield MP, Kulkarni K, Wohlgemuth J, Cobble M, Luttmann-Gibson H, Li C, Nelson JR, Cook NR, Buring JE, Krauss RM, Manson JE, Mora S

The impact of adjusting for baseline in pharmacogenomic genome-wide association studies of quantitative change.

NPJ genomic medicine

Oni-Orisan A, Haldar T, Ranatunga DK, Medina MW, Schaefer C, Krauss RM, Iribarren C, Risch N, Hoffmann TJ

Role of angiopoietin-like protein 3 in sugar-induced dyslipidemia in rhesus macaques: suppression by fish oil or RNAi.

Journal of lipid research

Butler AA, Graham JL, Stanhope KL, Wong S, King S, Bremer AA, Krauss RM, Hamilton J, Havel PJ

Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study.

The pharmacogenomics journal

Smit RAJ, Trompet S, Leong A, Goodarzi MO, Postmus I, Warren H, Theusch E, Barnes MR, Arsenault BJ, Li X, Feng Q, Chasman DI, Cupples LA, Hitman GA, Krauss RM, Psaty BM, Rotter JI, Cessie SL, Stein CM, Jukema JW

Expanding Precompetitive Multisector Collaborations to Advance Drug Development and Pharmacogenomics.

Clinical pharmacology and therapeutics

Yee SW, Do TP, Huang SM, Krauss RM, Kusuhara H, Sugiyama Y, Unadkat JD, Giacomini KM

ATP synthase inhibitory factor 1 (IF1), a novel myokine, regulates glucose metabolism by AMPK and Akt dual pathways.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Lee HJ, Moon J, Chung I, Chung JH, Park C, Lee JO, Han JA, Kang MJ, Yoo EH, Kwak SY, Jo G, Park W, Park J, Kim KM, Lim S, Ngoei KRW, Ling NXY, Oakhill JS, Galic S, Murray-Segal L, Kemp BE, Mantzoros CS, Krauss RM, Shin MJ, Kim HS

Lifestyle factors and high-risk atherosclerosis: Pathways and mechanisms beyond traditional risk factors.

European journal of preventive cardiology

Lechner K, von Schacky C, McKenzie AL, Worm N, Nixdorff U, Lechner B, Kränkel N, Halle M, Krauss RM, Scherr J

WHO draft guidelines on dietary saturated and trans fatty acids: time for a new approach?

BMJ (Clinical research ed.)

Astrup A, Bertram HC, Bonjour JP, de Groot LC, de Oliveira Otto MC, Feeney EL, Garg ML, Givens I, Kok FJ, Krauss RM, Lamarche B, Lecerf JM, Legrand P, McKinley M, Micha R, Michalski MC, Mozaffarian D, Soedamah-Muthu SS

Dietary carbohydrate restriction improves metabolic syndrome independent of weight loss.

JCI insight

Hyde PN, Sapper TN, Crabtree CD, LaFountain RA, Bowling ML, Buga A, Fell B, McSwiney FT, Dickerson RM, Miller VJ, Scandling D, Simonetti OP, Phinney SD, Kraemer WJ, King SA, Krauss RM, Volek JS

ApoC-III ASO Promotes Tissue LPL Activity in Absence of ApoE-Mediated TRL Clearance.

Journal of lipid research

Ramms B, Patel S, Nora C, Pessentheiner AR, Chang MW, Green CR, Golden GJ, Secrest P, Krauss RM, Metallo CM, Benner C, Alexander VJ, Witztum JL, Tsimikas S, Esko JD, Gordts PLSM

Low plasma adropin concentrations increase risks of weight gain and metabolic dysregulation in response to a high-sugar diet in male nonhuman primates.

The Journal of biological chemistry

Butler AA, Zhang J, Price CA, Stevens JR, Graham JL, Stanhope KL, King S, Krauss RM, Bremer AA, Havel PJ

Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation.

Stem cell research

Kuang YL, Munoz A, Nalula G, Santostefano KE, Sanghez V, Sanchez G, Terada N, Mattis AN, Iacovino M, Iribarren C, Krauss RM, Medina MW

Relationship between resolution of non-alcoholic steatohepatitis and changes in lipoprotein sub-fractions: a post-hoc analysis of the PIVENS trial.

Alimentary pharmacology & therapeutics

Corey KE, Wilson LA, Altinbas A, Yates KP, Kleiner DE, Chung RT, Krauss RM, Chalasani N

Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women.

European heart journal

Wang Z, Bergeron N, Levison BS, Li XS, Chiu S, Jia X, Koeth RA, Li L, Wu Y, Tang WHW, Krauss RM, Hazen SL

Fructose-induced hypertriglyceridemia in rhesus macaques is attenuated with fish oil or apoC3 RNA interference.

Journal of lipid research

Butler AA, Price CA, Graham JL, Stanhope KL, King S, Hung YH, Sethupathy P, Wong S, Hamilton J, Krauss RM, Bremer AA, Havel PJ

Bidirectional Mendelian randomization to explore the causal relationships between body mass index and polycystic ovary syndrome.

Human reproduction (Oxford, England)

Brower MA, Hai Y, Jones MR, Guo X, Chen YI, Rotter JI, Krauss RM, Legro RS, Azziz R, Goodarzi MO

Low-Density Lipoprotein Particle Size Subfractions and Cerebral Amyloidosis.

Journal of Alzheimer's disease : JAD

Lee S, Parekh T, King SM, Reed B, Chui HC, Krauss RM, Yassine HN

Single-molecule 3D imaging of human plasma intermediate-density lipoproteins reveals a polyhedral structure.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Lei D, Yu Y, Kuang YL, Liu J, Krauss RM, Ren G

Impact of Individual Traits, Saturated Fat, and Protein Source on the Gut Microbiome.

mBio

Lang JM, Pan C, Cantor RM, Tang WHW, Garcia-Garcia JC, Kurtz I, Hazen SL, Bergeron N, Krauss RM, Lusis AJ

Metagenomic Insights into the Degradation of Resistant Starch by Human Gut Microbiota.

Applied and environmental microbiology

Vital M, Howe A, Bergeron N, Krauss RM, Jansson JK, Tiedje JM

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

American journal of human genetics

Ligthart S, Vaez A, Võsa U, Stathopoulou MG, de Vries PS, Prins BP, Van der Most PJ, Tanaka T, Naderi E, Rose LM, Wu Y, Karlsson R, Barbalic M, Lin H, Pool R, Zhu G, Macé A, Sidore C, Trompet S, Mangino M, Sabater-Lleal M, Kemp JP, Abbasi A, Kacprowski T, Verweij N, Smith AV, Huang T, Marzi C, Feitosa MF, Lohman KK, Kleber ME, Milaneschi Y, Mueller C, Huq M, Vlachopoulou E, Lyytikäinen LP, Oldmeadow C, Deelen J, Perola M, Zhao JH, Feenstra B, Amini M, Lahti J, Schraut KE, Fornage M, Suktitipat B, Chen WM, Li X, Nutile T, Malerba G, Luan J, Bak T, Schork N, Del Greco M F, Thiering E, Mahajan A, Marioni RE, Mihailov E, Eriksson J, Ozel AB, Zhang W, Nethander M, Cheng YC, Aslibekyan S, Ang W, Gandin I, Yengo L, Portas L, Kooperberg C, Hofer E, Rajan KB, Schurmann C, den Hollander W, Ahluwalia TS, Zhao J, Draisma HHM, Ford I, Timpson N, Teumer A, Huang H, Wahl S, Liu Y, Huang J, Uh HW, Geller F, Joshi PK, Yanek LR, Trabetti E, Lehne B, Vozzi D, Verbanck M, Biino G, Saba Y, Meulenbelt I, O'Connell JR, Laakso M, Giulianini F, Magnusson PKE, Ballantyne CM, Hottenga JJ, Montgomery GW, Rivadineira F, Rueedi R, Steri M, Herzig KH, Stott DJ, Menni C, Frånberg M, St Pourcain B, Felix SB, Pers TH, Bakker SJL, Kraft P, Peters A, Vaidya D, Delgado G, Smit JH, Großmann V, Sinisalo J, Seppälä I, Williams SR, Holliday EG, Moed M, Langenberg C, Räikkönen K, Ding J, Campbell H, Sale MM, Chen YI, James AL, Ruggiero D, Soranzo N, Hartman CA, Smith EN, Berenson GS, Fuchsberger C, Hernandez D, Tiesler CMT, Giedraitis V, Liewald D, Fischer K, Mellström D, Larsson A, Wang Y, Scott WR, Lorentzon M, Beilby J, Ryan KA, Pennell CE, Vuckovic D, Balkau B, Concas MP, Schmidt R, Mendes de Leon CF, Bottinger EP, Kloppenburg M, Paternoster L, Boehnke M, Musk AW, Willemsen G, Evans DM, Madden PAF, Kähönen M, Kutalik Z, Zoledziewska M, Karhunen V, Kritchevsky SB, Sattar N, Lachance G, Clarke R, Harris TB, Raitakari OT, Attia JR, van Heemst D, Kajantie E, Sorice R, Gambaro G, Scott RA, Hicks AA, Ferrucci L, Standl M, Lindgren CM, Starr JM, Karlsson M, Lind L, Li JZ, Chambers JC, Mori TA, de Geus EJCN, Heath AC, Martin NG, Auvinen J, Buckley BM, de Craen AJM, Waldenberger M, Strauch K, Meitinger T, Scott RJ, McEvoy M, Beekman M, Bombieri C, Ridker PM, Mohlke KL, Pedersen NL, Morrison AC, Boomsma DI, Whitfield JB, Strachan DP, Hofman A, Vollenweider P, Cucca F, Jarvelin MR, Jukema JW, Spector TD, Hamsten A, Zeller T, Uitterlinden AG, Nauck M, Gudnason V, Qi L, Grallert H, Borecki IB, Rotter JI, März W, Wild PS, Lokki ML, Boyle M, Salomaa V, Melbye M, Eriksson JG, Wilson JF, Penninx BWJH, Becker DM, Worrall BB, Gibson G, Krauss RM, Ciullo M, Zaza G, Wareham NJ, Oldehinkel AJ, Palmer LJ, Murray SS, Pramstaller PP, Bandinelli S, Heinrich J, Ingelsson E, Deary IJ, Mägi R, Vandenput L, van der Harst P, Desch KC, Kooner JS, Ohlsson C, Hayward C, Lehtimäki T, Shuldiner AR, Arnett DK, Beilin LJ, Robino A, Froguel P, Pirastu M, Jess T, Koenig W, Loos RJF, Evans DA, Schmidt H, Smith GD, Slagboom PE, Eiriksdottir G, Morris AP, Psaty BM, Tracy RP, Nolte IM, Boerwinkle E, Visvikis-Siest S, Reiner AP, Gross M, Bis JC, Franke L, Franco OH, Benjamin EJ, Chasman DI, Dupuis J, Snieder H, Dehghan A, Alizadeh BZ

LPA Variants Are Associated With Residual Cardiovascular Risk in Patients Receiving Statins.

Circulation

Wei WQ, Li X, Feng Q, Kubo M, Kullo IJ, Peissig PL, Karlson EW, Jarvik GP, Lee MTM, Shang N, Larson EA, Edwards T, Shaffer CM, Mosley JD, Maeda S, Horikoshi M, Ritchie M, Williams MS, Larson EB, Crosslin DR, Bland ST, Pacheco JA, Rasmussen-Torvik LJ, Cronkite D, Hripcsak G, Cox NJ, Wilke RA, Stein CM, Rotter JI, Momozawa Y, Roden DM, Krauss RM, Denny JC

Characterization of Statin Low-Density Lipoprotein Cholesterol Dose-Response Using Electronic Health Records in a Large Population-Based Cohort.

Circulation. Genomic and precision medicine

Oni-Orisan A, Hoffmann TJ, Ranatunga D, Medina MW, Jorgenson E, Schaefer C, Krauss RM, Iribarren C, Risch N

ZNF542P is a pseudogene associated with LDL response to simvastatin treatment.

Scientific reports

Kim K, Theusch E, Kuang YL, Dose A, Mitchel K, Cubitt C, Chen YI, Krauss RM, Medina MW

Comparability of Lipoprotein Particle Number Concentrations Across ES-DMA, NMR, LC-MS/MS, Immunonephelometry, and VAP: In Search of a Candidate Reference Measurement Procedure for apoB and non-HDL-P Standardization.

Clinical chemistry

Delatour V, Clouet-Foraison N, Gaie-Levrel F, Marcovina SM, Hoofnagle AN, Kuklenyik Z, Caulfield MP, Otvos JD, Krauss RM, Kulkarni KR, Contois JH, Remaley AT, Vesper HW, Cobbaert CM, Gillery P

Adverse effects of statin therapy: perception vs. the evidence - focus on glucose homeostasis, cognitive, renal and hepatic function, haemorrhagic stroke and cataract.

European heart journal

Mach F, Ray KK, Wiklund O, Corsini A, Catapano AL, Bruckert E, De Backer G, Hegele RA, Hovingh GK, Jacobson TA, Krauss RM, Laufs U, Leiter LA, März W, Nordestgaard BG, Raal FJ, Roden M, Santos RD, Stein EA, Stroes ES, Thompson PD, Tokgözoglu L, Vladutiu GD, Gencer B, Stock JK, Ginsberg HN, Chapman MJ

Dietary fat and cardiometabolic health: evidence, controversies, and consensus for guidance.

BMJ (Clinical research ed.)

Forouhi NG, Krauss RM, Taubes G, Willett W

Pathways and mechanisms linking dietary components to cardiometabolic disease: thinking beyond calories.

Obesity reviews : an official journal of the International Association for the Study of Obesity

Stanhope KL, Goran MI, Bosy-Westphal A, King JC, Schmidt LA, Schwarz JM, Stice E, Sylvetsky AC, Turnbaugh PJ, Bray GA, Gardner CD, Havel PJ, Malik V, Mason AE, Ravussin E, Rosenbaum M, Welsh JA, Allister-Price C, Sigala DM, Greenwood MRC, Astrup A, Krauss RM

Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content.

PLoS biology

Liang X, Yee SW, Chien HC, Chen EC, Luo Q, Zou L, Piao M, Mifune A, Chen L, Calvert ME, King S, Norheim F, Abad J, Krauss RM, Giacomini KM

A large electronic-health-record-based genome-wide study of serum lipids.

Nature genetics

Hoffmann TJ, Theusch E, Haldar T, Ranatunga DK, Jorgenson E, Medina MW, Kvale MN, Kwok PY, Schaefer C, Krauss RM, Iribarren C, Risch N

Impact of Dietary Resistant Starch on the Human Gut Microbiome, Metaproteome, and Metabolome.

mBio

Maier TV, Lucio M, Lee LH, VerBerkmoes NC, Brislawn CJ, Bernhardt J, Lamendella R, McDermott JE, Bergeron N, Heinzmann SS, Morton JT, González A, Ackermann G, Knight R, Riedel K, Krauss RM, Schmitt-Kopplin P, Jansson JK

Assessing the mechanisms of cholesteryl ester transfer protein inhibitors.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Zhang M, Lei D, Peng B, Yang M, Zhang L, Charles MA, Rye KA, Krauss RM, Johns DG, Ren G

Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel.

European heart journal

Ference BA, Ginsberg HN, Graham I, Ray KK, Packard CJ, Bruckert E, Hegele RA, Krauss RM, Raal FJ, Schunkert H, Watts GF, Borén J, Fazio S, Horton JD, Masana L, Nicholls SJ, Nordestgaard BG, van de Sluis B, Taskinen MR, Tokgözoglu L, Landmesser U, Laufs U, Wiklund O, Stock JK, Chapman MJ, Catapano AL

New Pharmacogenomics Research Network: An Open Community Catalyzing Research and Translation in Precision Medicine.

Clinical pharmacology and therapeutics

Relling MV, Krauss RM, Roden DM, Klein TE, Fowler DM, Terada N, Lin L, Riel-Mehan M, Do TP, Kubo M, Yee SW, Johnson GT, Giacomini KM

Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity.

Nature

Saleheen D, Natarajan P, Armean IM, Zhao W, Rasheed A, Khetarpal SA, Won HH, Karczewski KJ, O'Donnell-Luria AH, Samocha KE, Weisburd B, Gupta N, Zaidi M, Samuel M, Imran A, Abbas S, Majeed F, Ishaq M, Akhtar S, Trindade K, Mucksavage M, Qamar N, Zaman KS, Yaqoob Z, Saghir T, Rizvi SNH, Memon A, Hayyat Mallick N, Ishaq M, Rasheed SZ, Memon FU, Mahmood K, Ahmed N, Do R, Krauss RM, MacArthur DG, Gabriel S, Lander ES, Daly MJ, Frossard P, Danesh J, Rader DJ, Kathiresan S

Odd Chain Fatty Acids; New Insights of the Relationship Between the Gut Microbiota, Dietary Intake, Biosynthesis and Glucose Intolerance.

Scientific reports

Jenkins BJ, Seyssel K, Chiu S, Pan PH, Lin SY, Stanley E, Ament Z, West JA, Summerhill K, Griffin JL, Vetter W, Autio KJ, Hiltunen K, Hazebrouck S, Stepankova R, Chen CJ, Alligier M, Laville M, Moore M, Kraft G, Cherrington A, King S, Krauss RM, de Schryver E, Van Veldhoven PP, Ronis M, Koulman A

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach.

PLoS medicine

Mendelson MM, Marioni RE, Joehanes R, Liu C, Hedman ÅK, Aslibekyan S, Demerath EW, Guan W, Zhi D, Yao C, Huan T, Willinger C, Chen B, Courchesne P, Multhaup M, Irvin MR, Cohain A, Schadt EE, Grove ML, Bressler J, North K, Sundström J, Gustafsson S, Shah S, McRae AF, Harris SE, Gibson J, Redmond P, Corley J, Murphy L, Starr JM, Kleinbrink E, Lipovich L, Visscher PM, Wray NR, Krauss RM, Fallin D, Feinberg A, Absher DM, Fornage M, Pankow JS, Lind L, Fox C, Ingelsson E, Arnett DK, Boerwinkle E, Liang L, Levy D, Deary IJ

Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies.

Circulation. Cardiovascular genetics

Hedman ÅK, Mendelson MM, Marioni RE, Gustafsson S, Joehanes R, Irvin MR, Zhi D, Sandling JK, Yao C, Liu C, Liang L, Huan T, McRae AF, Demissie S, Shah S, Starr JM, Cupples LA, Deloukas P, Spector TD, Sundström J, Krauss RM, Arnett DK, Deary IJ, Lind L, Levy D, Ingelsson E

Changes in low-density lipoprotein size phenotypes associate with changes in apolipoprotein C-III glycoforms after dietary interventions.

Journal of clinical lipidology

Mendoza S, Trenchevska O, King SM, Nelson RW, Nedelkov D, Krauss RM, Yassine HN

Pharmacometabolomic signature links simvastatin therapy and insulin resistance.

Metabolomics : Official journal of the Metabolomic Society

Elbadawi-Sidhu M, Baillie RA, Zhu H, Chen YI, Goodarzi MO, Rotter JI, Krauss RM, Fiehn O, Kaddurah-Daouk R

Diets high in resistant starch increase plasma levels of trimethylamine-N-oxide, a gut microbiome metabolite associated with CVD risk.

The British journal of nutrition

Bergeron N, Williams PT, Lamendella R, Faghihnia N, Grube A, Li X, Wang Z, Knight R, Jansson JK, Hazen SL, Krauss RM

Candidate-Gene Study of Functional Polymorphisms in SLCO1B1 and CYP3A4/5 and the Cholesterol-Lowering Response to Simvastatin.

Clinical and translational science

Kitzmiller JP, Luzum JA, Dauki A, Krauss RM, Medina MW

Rooted in risk: genetic predisposition for low-density lipoprotein cholesterol level associates with diminished low-density lipoprotein cholesterol response to statin treatment.

Pharmacogenomics

Smit RA, Postmus I, Trompet S, Barnes MR, Warren H, Arsenault BJ, Chasman DI, Cupples LA, Hitman GA, Krauss RM, Li X, Psaty BM, Stein CM, Rotter JI, Jukema JW

Which cheese to choose?

The American journal of clinical nutrition

Siri-Tarino PW, Krauss RM

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.

Nature genetics

Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J, Donnelly LA, Kanoni S, Petersen AK, Pihur V, Strawbridge RJ, Shungin D, Hughes MF, Meirelles O, Kaakinen M, Bouatia-Naji N, Kristiansson K, Shah S, Kleber ME, Guo X, Lyytikäinen LP, Fava C, Eriksson N, Nolte IM, Magnusson PK, Salfati EL, Rallidis LS, Theusch E, Smith AJP, Folkersen L, Witkowska K, Pers TH, Joehanes R, Kim SK, Lataniotis L, Jansen R, Johnson AD, Warren H, Kim YJ, Zhao W, Wu Y, Tayo BO, Bochud M, Absher D, Adair LS, Amin N, Arking DE, Axelsson T, Baldassarre D, Balkau B, Bandinelli S, Barnes MR, Barroso I, Bevan S, Bis JC, Bjornsdottir G, Boehnke M, Boerwinkle E, Bonnycastle LL, Boomsma DI, Bornstein SR, Brown MJ, Burnier M, Cabrera CP, Chambers JC, Chang IS, Cheng CY, Chines PS, Chung RH, Collins FS, Connell JM, Döring A, Dallongeville J, Danesh J, de Faire U, Delgado G, Dominiczak AF, Doney ASF, Drenos F, Edkins S, Eicher JD, Elosua R, Enroth S, Erdmann J, Eriksson P, Esko T, Evangelou E, Evans A, Fall T, Farrall M, Felix JF, Ferrières J, Ferrucci L, Fornage M, Forrester T, Franceschini N, Duran OHF, Franco-Cereceda A, Fraser RM, Ganesh SK, Gao H, Gertow K, Gianfagna F, Gigante B, Giulianini F, Goel A, Goodall AH, Goodarzi MO, Gorski M, Gräßler J, Groves C, Gudnason V, Gyllensten U, Hallmans G, Hartikainen AL, Hassinen M, Havulinna AS, Hayward C, Hercberg S, Herzig KH, Hicks AA, Hingorani AD, Hirschhorn JN, Hofman A, Holmen J, Holmen OL, Hottenga JJ, Howard P, Hsiung CA, Hunt SC, Ikram MA, Illig T, Iribarren C, Jensen RA, Kähönen M, Kang H, Kathiresan S, Keating BJ, Khaw KT, Kim YK, Kim E, Kivimaki M, Klopp N, Kolovou G, Komulainen P, Kooner JS, Kosova G, Krauss RM, Kuh D, Kutalik Z, Kuusisto J, Kvaløy K, Lakka TA, Lee NR, Lee IT, Lee WJ, Levy D, Li X, Liang KW, Lin H, Lin L, Lindström J, Lobbens S, Männistö S, Müller G, Müller-Nurasyid M, Mach F, Markus HS, Marouli E, McCarthy MI, McKenzie CA, Meneton P, Menni C, Metspalu A, Mijatovic V, Moilanen L, Montasser ME, Morris AD, Morrison AC, Mulas A, Nagaraja R, Narisu N, Nikus K, O'Donnell CJ, O'Reilly PF, Ong KK, Paccaud F, Palmer CD, Parsa A, Pedersen NL, Penninx BW, Perola M, Peters A, Poulter N, Pramstaller PP, Psaty BM, Quertermous T, Rao DC, Rasheed A, Rayner NWNWR, Renström F, Rettig R, Rice KM, Roberts R, Rose LM, Rossouw J, Samani NJ, Sanna S, Saramies J, Schunkert H, Sebert S, Sheu WH, Shin YA, Sim X, Smit JH, Smith AV, Sosa MX, Spector TD, Stancáková A, Stanton A, Stirrups KE, Stringham HM, Sundstrom J, Swift AJ, Syvänen AC, Tai ES, Tanaka T, Tarasov KV, Teumer A, Thorsteinsdottir U, Tobin MD, Tremoli E, Uitterlinden AG, Uusitupa M, Vaez A, Vaidya D, van Duijn CM, van Iperen EPA, Vasan RS, Verwoert GC, Virtamo J, Vitart V, Voight BF, Vollenweider P, Wagner A, Wain LV, Wareham NJ, Watkins H, Weder AB, Westra HJ, Wilks R, Wilsgaard T, Wilson JF, Wong TY, Yang TP, Yao J, Yengo L, Zhang W, Zhao JH, Zhu X, Bovet P, Cooper RS, Mohlke KL, Saleheen D, Lee JY, Elliott P, Gierman HJ, Willer CJ, Franke L, Hovingh GK, Taylor KD, Dedoussis G, Sever P, Wong A, Lind L, Assimes TL, Njølstad I, Schwarz PE, Langenberg C, Snieder H, Caulfield MJ, Melander O, Laakso M, Saltevo J, Rauramaa R, Tuomilehto J, Ingelsson E, Lehtimäki T, Hveem K, Palmas W, März W, Kumari M, Salomaa V, Chen YI, Rotter JI, Froguel P, Jarvelin MR, Lakatta EG, Kuulasmaa K, Franks PW, Hamsten A, Wichmann HE, Palmer CNA, Stefansson K, Ridker PM, Loos RJF, Chakravarti A, Deloukas P, Morris AP, Newton-Cheh C, Munroe PB

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins.

Journal of medical genetics

Postmus I, Warren HR, Trompet S, Arsenault BJ, Avery CL, Bis JC, Chasman DI, de Keyser CE, Deshmukh HA, Evans DS, Feng Q, Li X, Smit RA, Smith AV, Sun F, Taylor KD, Arnold AM, Barnes MR, Barratt BJ, Betteridge J, Boekholdt SM, Boerwinkle E, Buckley BM, Chen YI, de Craen AJ, Cummings SR, Denny JC, Dubé MP, Durrington PN, Eiriksdottir G, Ford I, Guo X, Harris TB, Heckbert SR, Hofman A, Hovingh GK, Kastelein JJ, Launer LJ, Liu CT, Liu Y, Lumley T, McKeigue PM, Munroe PB, Neil A, Nickerson DA, Nyberg F, O'Brien E, O'Donnell CJ, Post W, Poulter N, Vasan RS, Rice K, Rich SS, Rivadeneira F, Sattar N, Sever P, Shaw-Hawkins S, Shields DC, Slagboom PE, Smith NL, Smith JD, Sotoodehnia N, Stanton A, Stott DJ, Stricker BH, Stürmer T, Uitterlinden AG, Wei WQ, Westendorp RG, Whitsel EA, Wiggins KL, Wilke RA, Ballantyne CM, Colhoun HM, Cupples LA, Franco OH, Gudnason V, Hitman G, Palmer CN, Psaty BM, Ridker PM, Stafford JM, Stein CM, Tardif JC, Caulfield MJ, Jukema JW, Rotter JI, Krauss RM

Polyhedral 3D structure of human plasma very low density lipoproteins by individual particle cryo-electron tomography1.

Journal of lipid research

Yu Y, Kuang YL, Lei D, Zhai X, Zhang M, Krauss RM, Ren G

Diet, lipids, and cardiovascular disease.

Current opinion in lipidology

Siri-Tarino PW, Krauss RM

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin.

American journal of human genetics

Liu CT, Raghavan S, Maruthur N, Kabagambe EK, Hong J, Ng MC, Hivert MF, Lu Y, An P, Bentley AR, Drolet AM, Gaulton KJ, Guo X, Armstrong LL, Irvin MR, Li M, Lipovich L, Rybin DV, Taylor KD, Agyemang C, Palmer ND, Cade BE, Chen WM, Dauriz M, Delaney JA, Edwards TL, Evans DS, Evans MK, Lange LA, Leong A, Liu J, Liu Y, Nayak U, Patel SR, Porneala BC, Rasmussen-Torvik LJ, Snijder MB, Stallings SC, Tanaka T, Yanek LR, Zhao W, Becker DM, Bielak LF, Biggs ML, Bottinger EP, Bowden DW, Chen G, Correa A, Couper DJ, Crawford DC, Cushman M, Eicher JD, Fornage M, Franceschini N, Fu YP, Goodarzi MO, Gottesman O, Hara K, Harris TB, Jensen RA, Johnson AD, Jhun MA, Karter AJ, Keller MF, Kho AN, Kizer JR, Krauss RM, Langefeld CD, Li X, Liang J, Liu S, Lowe WL, Mosley TH, North KE, Pacheco JA, Peyser PA, Patrick AL, Rice KM, Selvin E, Sims M, Smith JA, Tajuddin SM, Vaidya D, Wren MP, Yao J, Zhu X, Ziegler JT, Zmuda JM, Zonderman AB, Zwinderman AH, Adeyemo A, Boerwinkle E, Ferrucci L, Hayes MG, Kardia SL, Miljkovic I, Pankow JS, Rotimi CN, Sale MM, Wagenknecht LE, Arnett DK, Chen YD, Nalls MA, Province MA, Kao WH, Siscovick DS, Psaty BM, Wilson JG, Loos RJ, Dupuis J, Rich SS, Florez JC, Rotter JI, Morris AP, Meigs JB

Prepregnancy Adverse Lipid Profile and Subsequent Risk of Gestational Diabetes.

The Journal of clinical endocrinology and metabolism

Han ES, Krauss RM, Xu F, Sridhar SB, Ferrara A, Quesenberry CP, Hedderson MM

Association between disease occurrence and fertility of dairy cows in three geographic regions of Chile.

Theriogenology

Pinedo PJ, Melendez P, Paudyal S, Krauss R, Arias F, Lopez H, Luco A, Vergara CF

PharmGKB summary: very important pharmacogene information for RYR1.

Pharmacogenetics and genomics

Alvarellos ML, Krauss RM, Wilke RA, Altman RB, Klein TE

Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines.

The pharmacogenomics journal

Chhibber A, French CE, Yee SW, Gamazon ER, Theusch E, Qin X, Webb A, Papp AC, Wang A, Simmons CQ, Konkashbaev A, Chaudhry AS, Mitchel K, Stryke D, Ferrin TE, Weiss ST, Kroetz DL, Sadee W, Nickerson DA, Krauss RM, George AL, Schuetz EG, Medina MW, Cox NJ, Scherer SE, Giacomini KM, Brenner SE

Does Milk Consumption Contribute to Cardiometabolic Health and Overall Diet Quality?

The Canadian journal of cardiology

Lamarche B, Givens DI, Soedamah-Muthu S, Krauss RM, Jakobsen MU, Bischoff-Ferrari HA, Pan A, Després JP

In Memoriam: Alexander V. Nichols (1924 – 2015).

Journal of lipid research

Forte TM, Krauss RM

Association study of androgen signaling pathway genes in polycystic ovary syndrome.

Fertility and sterility

Ketefian A, Jones MR, Krauss RM, Chen YD, Legro RS, Azziz R, Goodarzi MO

Food Consumption and its Impact on Cardiovascular Disease: Importance of Solutions Focused on the Globalized Food System: A Report From the Workshop Convened by the World Heart Federation.

Journal of the American College of Cardiology

Anand SS, Hawkes C, de Souza RJ, Mente A, Dehghan M, Nugent R, Zulyniak MA, Weis T, Bernstein AM, Krauss RM, Kromhout D, Jenkins DJA, Malik V, Martinez-Gonzalez MA, Mozaffarian D, Yusuf S, Willett WC, Popkin BM

Endogenous Sex Steroid Hormones, Lipid Subfractions, and Ectopic Adiposity in Asian Indians.

Metabolic syndrome and related disorders

Kim C, Kong S, Krauss RM, Stanczyk FZ, Reddy ST, Needham BL, Kanaya AM

Individual and Combined Associations of Genetic Variants in CYP3A4, CYP3A5, and SLCO1B1 With Simvastatin and Simvastatin Acid Plasma Concentrations.

Journal of cardiovascular pharmacology

Luzum JA, Theusch E, Taylor KD, Wang A, Sadee W, Binkley PF, Krauss RM, Medina MW, Kitzmiller JP

Low-Density Lipoprotein Particle Number Is Associated With Cardiovascular Events Among Those Not Classified Into Statin Benefit Groups.

Journal of the American College of Cardiology

Melander O, Shiffman D, Caulfield MP, Louie JZ, Rowland CM, Devlin JJ, Krauss RM

A multicomponent nutrient bar promotes weight loss and improves dyslipidemia and insulin resistance in the overweight/obese: chronic inflammation blunts these improvements.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

McCann JC, Shigenaga MK, Mietus-Snyder ML, Lal A, Suh JH, Krauss RM, Gildengorin GL, Goldrich AM, Block DS, Shenvi SV, McHugh TH, Olson DA, Ames BN

A multivariate genome-wide association analysis of 10 LDL subfractions, and their response to statin treatment, in 1868 Caucasians.

PloS one

Shim H, Chasman DI, Smith JD, Mora S, Ridker PM, Nickerson DA, Krauss RM, Stephens M

Statin-associated muscle symptoms: impact on statin therapy-European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management.

European heart journal

Stroes ES, Thompson PD, Corsini A, Vladutiu GD, Raal FJ, Ray KK, Roden M, Stein E, Tokgözoglu L, Nordestgaard BG, Bruckert E, De Backer G, Krauss RM, Laufs U, Santos RD, Hegele RA, Hovingh GK, Leiter LA, Mach F, März W, Newman CB, Wiklund O, Jacobson TA, Catapano AL, Chapman MJ, Ginsberg HN

Further investigation in europeans of susceptibility variants for polycystic ovary syndrome discovered in genome-wide association studies of Chinese individuals.

The Journal of clinical endocrinology and metabolism

Brower MA, Jones MR, Rotter JI, Krauss RM, Legro RS, Azziz R, Goodarzi MO

Genetic variation in the UGT1A locus is associated with simvastatin efficacy in a clinical practice setting.

Pharmacogenomics

Iwuchukwu OF, Feng Q, Wei WQ, Jiang L, Jiang M, Xu H, Denny JC, Wilke RA, Krauss RM, Roden DM, Stein CM

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.

Nature communications

Postmus I, Trompet S, Deshmukh HA, Barnes MR, Li X, Warren HR, Chasman DI, Zhou K, Arsenault BJ, Donnelly LA, Wiggins KL, Avery CL, Griffin P, Feng Q, Taylor KD, Li G, Evans DS, Smith AV, de Keyser CE, Johnson AD, de Craen AJ, Stott DJ, Buckley BM, Ford I, Westendorp RG, Slagboom PE, Sattar N, Munroe PB, Sever P, Poulter N, Stanton A, Shields DC, O'Brien E, Shaw-Hawkins S, Chen YD, Nickerson DA, Smith JD, Dubé MP, Boekholdt SM, Hovingh GK, Kastelein JJ, McKeigue PM, Betteridge J, Neil A, Durrington PN, Doney A, Carr F, Morris A, McCarthy MI, Groop L, Ahlqvist E, Bis JC, Rice K, Smith NL, Lumley T, Whitsel EA, Stürmer T, Boerwinkle E, Ngwa JS, O'Donnell CJ, Vasan RS, Wei WQ, Wilke RA, Liu CT, Sun F, Guo X, Heckbert SR, Post W, Sotoodehnia N, Arnold AM, Stafford JM, Ding J, Herrington DM, Kritchevsky SB, Eiriksdottir G, Launer LJ, Harris TB, Chu AY, Giulianini F, MacFadyen JG, Barratt BJ, Nyberg F, Stricker BH, Uitterlinden AG, Hofman A, Rivadeneira F, Emilsson V, Franco OH, Ridker PM, Gudnason V, Liu Y, Denny JC, Ballantyne CM, Rotter JI, Adrienne Cupples L, Psaty BM, Palmer CN, Tardif JC, Colhoun HM, Hitman G, Krauss RM, Wouter Jukema J, Caulfield MJ

Ancestry and other genetic associations with plasma PCSK9 response to simvastatin.

Pharmacogenetics and genomics

Theusch E, Medina MW, Rotter JI, Krauss RM

Prediction of LDL cholesterol response to statin using transcriptomic and genetic variation.

Genome biology

Kim K, Bolotin E, Theusch E, Huang H, Medina MW, Krauss RM

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.

Lancet (London, England)

Swerdlow DI, Preiss D, Kuchenbaecker KB, Holmes MV, Engmann JE, Shah T, Sofat R, Stender S, Johnson PC, Scott RA, Leusink M, Verweij N, Sharp SJ, Guo Y, Giambartolomei C, Chung C, Peasey A, Amuzu A, Li K, Palmen J, Howard P, Cooper JA, Drenos F, Li YR, Lowe G, Gallacher J, Stewart MC, Tzoulaki I, Buxbaum SG, van der A DL, Forouhi NG, Onland-Moret NC, van der Schouw YT, Schnabel RB, Hubacek JA, Kubinova R, Baceviciene M, Tamosiunas A, Pajak A, Topor-Madry R, Stepaniak U, Malyutina S, Baldassarre D, Sennblad B, Tremoli E, de Faire U, Veglia F, Ford I, Jukema JW, Westendorp RG, de Borst GJ, de Jong PA, Algra A, Spiering W, Maitland-van der Zee AH, Klungel OH, de Boer A, Doevendans PA, Eaton CB, Robinson JG, Duggan D, Kjekshus J, Downs JR, Gotto AM, Keech AC, Marchioli R, Tognoni G, Sever PS, Poulter NR, Waters DD, Pedersen TR, Amarenco P, Nakamura H, McMurray JJ, Lewsey JD, Chasman DI, Ridker PM, Maggioni AP, Tavazzi L, Ray KK, Seshasai SR, Manson JE, Price JF, Whincup PH, Morris RW, Lawlor DA, Smith GD, Ben-Shlomo Y, Schreiner PJ, Fornage M, Siscovick DS, Cushman M, Kumari M, Wareham NJ, Verschuren WM, Redline S, Patel SR, Whittaker JC, Hamsten A, Delaney JA, Dale C, Gaunt TR, Wong A, Kuh D, Hardy R, Kathiresan S, Castillo BA, van der Harst P, Brunner EJ, Tybjaerg-Hansen A, Marmot MG, Krauss RM, Tsai M, Coresh J, Hoogeveen RC, Psaty BM, Lange LA, Hakonarson H, Dudbridge F, Humphries SE, Talmud PJ, Kivimäki M, Timpson NJ, Langenberg C, Asselbergs FW, Voevoda M, Bobak M, Pikhart H, Wilson JG, Reiner AP, Keating BJ, Hingorani AD, Sattar N

Mangravite et al. reply.

Nature

Mangravite LM, Engelhardt BE, Stephens M, Krauss RM

Diets high in protein or saturated fat do not affect insulin sensitivity or plasma concentrations of lipids and lipoproteins in overweight and obese adults.

The Journal of nutrition

Chiu S, Williams PT, Dawson T, Bergman RN, Stefanovski D, Watkins SM, Krauss RM

Transmembrane protein 55B is a novel regulator of cellular cholesterol metabolism.

Arteriosclerosis, thrombosis, and vascular biology

Medina MW, Bauzon F, Naidoo D, Theusch E, Stevens K, Schilde J, Schubert C, Mangravite LM, Rudel LL, Temel RE, Runz H, Krauss RM

Nonalcoholic steatohepatitis is associated with an atherogenic lipoprotein subfraction profile.

Lipids in health and disease

Corey KE, Misdraji J, Gelrud L, Zheng H, Chung RT, Krauss RM

The clinical pharmacogenetics implementation consortium guideline for SLCO1B1 and simvastatin-induced myopathy: 2014 update.

Clinical pharmacology and therapeutics

Ramsey LB, Johnson SG, Caudle KE, Haidar CE, Voora D, Wilke RA, Maxwell WD, McLeod HL, Krauss RM, Roden DM, Feng Q, Cooper-DeHoff RM, Gong L, Klein TE, Wadelius M, Niemi M

All low-density lipoprotein particles are not created equal.

Arteriosclerosis, thrombosis, and vascular biology

Krauss RM

Organophosphorus flame retardants inhibit specific liver carboxylesterases and cause serum hypertriglyceridemia.

ACS chemical biology

Morris PJ, Medina-Cleghorn D, Heslin A, King SM, Orr J, Mulvihill MM, Krauss RM, Nomura DK

Genome-wide association and pharmacological profiling of 29 anticancer agents using lymphoblastoid cell lines.

Pharmacogenomics

Brown CC, Havener TM, Medina MW, Jack JR, Krauss RM, McLeod HL, Motsinger-Reif AA

SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease.

Cell reports

Shin J, He M, Liu Y, Paredes S, Villanova L, Brown K, Qiu X, Nabavi N, Mohrin M, Wojnoonski K, Li P, Cheng HL, Murphy AJ, Valenzuela DM, Luo H, Kapahi P, Krauss R, Mostoslavsky R, Yancopoulos GD, Alt FW, Chua KF, Chen D

Statin-induced changes in gene expression in EBV-transformed and native B-cells.

Human molecular genetics

Bolotin E, Armendariz A, Kim K, Heo SJ, Boffelli D, Tantisira K, Rotter JI, Krauss RM, Medina MW

Common variants associated with plasma triglycerides and risk for coronary artery disease.

Nature genetics

Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A, Den Hertog HM, Donnelly LA, Ehret GB, Esko T, Feitosa MF, Ferreira T, Fischer K, Fontanillas P, Fraser RM, Freitag DF, Gurdasani D, Heikkilä K, Hyppönen E, Isaacs A, Jackson AU, Johansson A, Johnson T, Kaakinen M, Kettunen J, Kleber ME, Li X, Luan J, Lyytikäinen LP, Magnusson PK, Mangino M, Mihailov E, Montasser ME, Müller-Nurasyid M, Nolte IM, O'Connell JR, Palmer CD, Perola M, Petersen AK, Sanna S, Saxena R, Service SK, Shah S, Shungin D, Sidore C, Song C, Strawbridge RJ, Surakka I, Tanaka T, Teslovich TM, Thorleifsson G, Van den Herik EG, Voight BF, Volcik KA, Waite LL, Wong A, Wu Y, Zhang W, Absher D, Asiki G, Barroso I, Been LF, Bolton JL, Bonnycastle LL, Brambilla P, Burnett MS, Cesana G, Dimitriou M, Doney AS, Döring A, Elliott P, Epstein SE, Eyjolfsson GI, Gigante B, Goodarzi MO, Grallert H, Gravito ML, Groves CJ, Hallmans G, Hartikainen AL, Hayward C, Hernandez D, Hicks AA, Holm H, Hung YJ, Illig T, Jones MR, Kaleebu P, Kastelein JJ, Khaw KT, Kim E, Klopp N, Komulainen P, Kumari M, Langenberg C, Lehtimäki T, Lin SY, Lindström J, Loos RJ, Mach F, McArdle WL, Meisinger C, Mitchell BD, Müller G, Nagaraja R, Narisu N, Nieminen TV, Nsubuga RN, Olafsson I, Ong KK, Palotie A, Papamarkou T, Pomilla C, Pouta A, Rader DJ, Reilly MP, Ridker PM, Rivadeneira F, Rudan I, Ruokonen A, Samani N, Scharnagl H, Seeley J, Silander K, Stancáková A, Stirrups K, Swift AJ, Tiret L, Uitterlinden AG, van Pelt LJ, Vedantam S, Wainwright N, Wijmenga C, Wild SH, Willemsen G, Wilsgaard T, Wilson JF, Young EH, Zhao JH, Adair LS, Arveiler D, Assimes TL, Bandinelli S, Bennett F, Bochud M, Boehm BO, Boomsma DI, Borecki IB, Bornstein SR, Bovet P, Burnier M, Campbell H, Chakravarti A, Chambers JC, Chen YD, Collins FS, Cooper RS, Danesh J, Dedoussis G, de Faire U, Feranil AB, Ferrières J, Ferrucci L, Freimer NB, Gieger C, Groop LC, Gudnason V, Gyllensten U, Hamsten A, Harris TB, Hingorani A, Hirschhorn JN, Hofman A, Hovingh GK, Hsiung CA, Humphries SE, Hunt SC, Hveem K, Iribarren C, Järvelin MR, Jula A, Kähönen M, Kaprio J, Kesäniemi A, Kivimaki M, Kooner JS, Koudstaal PJ, Krauss RM, Kuh D, Kuusisto J, Kyvik KO, Laakso M, Lakka TA, Lind L, Lindgren CM, Martin NG, März W, McCarthy MI, McKenzie CA, Meneton P, Metspalu A, Moilanen L, Morris AD, Munroe PB, Njølstad I, Pedersen NL, Power C, Pramstaller PP, Price JF, Psaty BM, Quertermous T, Rauramaa R, Saleheen D, Salomaa V, Sanghera DK, Saramies J, Schwarz PE, Sheu WH, Shuldiner AR, Siegbahn A, Spector TD, Stefansson K, Strachan DP, Tayo BO, Tremoli E, Tuomilehto J, Uusitupa M, van Duijn CM, Vollenweider P, Wallentin L, Wareham NJ, Whitfield JB, Wolffenbuttel BH, Altshuler D, Ordovas JM, Boerwinkle E, Palmer CN, Thorsteinsdottir U, Chasman DI, Rotter JI, Franks PW, Ripatti S, Cupples LA, Sandhu MS, Rich SS, Boehnke M, Deloukas P, Mohlke KL, Ingelsson E, Abecasis GR, Daly MJ, Neale BM, Kathiresan S

Discovery and refinement of loci associated with lipid levels.

Nature genetics

Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A, Den Hertog HM, Do R, Donnelly LA, Ehret GB, Esko T, Feitosa MF, Ferreira T, Fischer K, Fontanillas P, Fraser RM, Freitag DF, Gurdasani D, Heikkilä K, Hyppönen E, Isaacs A, Jackson AU, Johansson Å, Johnson T, Kaakinen M, Kettunen J, Kleber ME, Li X, Luan J, Lyytikäinen LP, Magnusson PKE, Mangino M, Mihailov E, Montasser ME, Müller-Nurasyid M, Nolte IM, O'Connell JR, Palmer CD, Perola M, Petersen AK, Sanna S, Saxena R, Service SK, Shah S, Shungin D, Sidore C, Song C, Strawbridge RJ, Surakka I, Tanaka T, Teslovich TM, Thorleifsson G, Van den Herik EG, Voight BF, Volcik KA, Waite LL, Wong A, Wu Y, Zhang W, Absher D, Asiki G, Barroso I, Been LF, Bolton JL, Bonnycastle LL, Brambilla P, Burnett MS, Cesana G, Dimitriou M, Doney ASF, Döring A, Elliott P, Epstein SE, Ingi Eyjolfsson G, Gigante B, Goodarzi MO, Grallert H, Gravito ML, Groves CJ, Hallmans G, Hartikainen AL, Hayward C, Hernandez D, Hicks AA, Holm H, Hung YJ, Illig T, Jones MR, Kaleebu P, Kastelein JJP, Khaw KT, Kim E, Klopp N, Komulainen P, Kumari M, Langenberg C, Lehtimäki T, Lin SY, Lindström J, Loos RJF, Mach F, McArdle WL, Meisinger C, Mitchell BD, Müller G, Nagaraja R, Narisu N, Nieminen TVM, Nsubuga RN, Olafsson I, Ong KK, Palotie A, Papamarkou T, Pomilla C, Pouta A, Rader DJ, Reilly MP, Ridker PM, Rivadeneira F, Rudan I, Ruokonen A, Samani N, Scharnagl H, Seeley J, Silander K, Stancáková A, Stirrups K, Swift AJ, Tiret L, Uitterlinden AG, van Pelt LJ, Vedantam S, Wainwright N, Wijmenga C, Wild SH, Willemsen G, Wilsgaard T, Wilson JF, Young EH, Zhao JH, Adair LS, Arveiler D, Assimes TL, Bandinelli S, Bennett F, Bochud M, Boehm BO, Boomsma DI, Borecki IB, Bornstein SR, Bovet P, Burnier M, Campbell H, Chakravarti A, Chambers JC, Chen YI, Collins FS, Cooper RS, Danesh J, Dedoussis G, de Faire U, Feranil AB, Ferrières J, Ferrucci L, Freimer NB, Gieger C, Groop LC, Gudnason V, Gyllensten U, Hamsten A, Harris TB, Hingorani A, Hirschhorn JN, Hofman A, Hovingh GK, Hsiung CA, Humphries SE, Hunt SC, Hveem K, Iribarren C, Järvelin MR, Jula A, Kähönen M, Kaprio J, Kesäniemi A, Kivimaki M, Kooner JS, Koudstaal PJ, Krauss RM, Kuh D, Kuusisto J, Kyvik KO, Laakso M, Lakka TA, Lind L, Lindgren CM, Martin NG, März W, McCarthy MI, McKenzie CA, Meneton P, Metspalu A, Moilanen L, Morris AD, Munroe PB, Njølstad I, Pedersen NL, Power C, Pramstaller PP, Price JF, Psaty BM, Quertermous T, Rauramaa R, Saleheen D, Salomaa V, Sanghera DK, Saramies J, Schwarz PEH, Sheu WH, Shuldiner AR, Siegbahn A, Spector TD, Stefansson K, Strachan DP, Tayo BO, Tremoli E, Tuomilehto J, Uusitupa M, van Duijn CM, Vollenweider P, Wallentin L, Wareham NJ, Whitfield JB, Wolffenbuttel BHR, Ordovas JM, Boerwinkle E, Palmer CNA, Thorsteinsdottir U, Chasman DI, Rotter JI, Franks PW, Ripatti S, Cupples LA, Sandhu MS, Rich SS, Boehnke M, Deloukas P, Kathiresan S, Mohlke KL, Ingelsson E, Abecasis GR

Characterization of statin dose response in electronic medical records.

Clinical pharmacology and therapeutics

Wei WQ, Feng Q, Jiang L, Waitara MS, Iwuchukwu OF, Roden DM, Jiang M, Xu H, Krauss RM, Rotter JI, Nickerson DA, Davis RL, Berg RL, Peissig PL, McCarty CA, Wilke RA, Denny JC

A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.

Nature

Mangravite LM, Engelhardt BE, Medina MW, Smith JD, Brown CD, Chasman DI, Mecham BH, Howie B, Shim H, Naidoo D, Feng Q, Rieder MJ, Chen YD, Rotter JI, Ridker PM, Hopewell JC, Parish S, Armitage J, Collins R, Wilke RA, Nickerson DA, Stephens M, Krauss RM

Pharmacometabolomics of statin response.

Clinical pharmacology and therapeutics

Krauss RM, Zhu H, Kaddurah-Daouk R

High-density lipoproteins: a consensus statement from the National Lipid Association.

Journal of clinical lipidology

Toth PP, Barter PJ, Rosenson RS, Boden WE, Chapman MJ, Cuchel M, D'Agostino RB, Davidson MH, Davidson WS, Heinecke JW, Karas RH, Kontush A, Krauss RM, Miller M, Rader DJ

Relationship of sex to diabetes risk in statin trials.

Diabetes care

Goodarzi MO, Li X, Krauss RM, Rotter JI, Chen YD

Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.

Nature medicine

Koeth RA, Wang Z, Levison BS, Buffa JA, Org E, Sheehy BT, Britt EB, Fu X, Wu Y, Li L, Smith JD, DiDonato JA, Chen J, Li H, Wu GD, Lewis JD, Warrier M, Brown JM, Krauss RM, Tang WH, Bushman FD, Lusis AJ, Hazen SL

Alternative splicing in the regulation of cholesterol homeostasis.

Current opinion in lipidology

Medina MW, Krauss RM

A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function.

Human molecular genetics

Gao F, Ihn HE, Medina MW, Krauss RM

ATHENA: a tool for meta-dimensional analysis applied to genotypes and gene expression data to predict HDL cholesterol levels.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing

Holzinger ER, Dudek SM, Frase AT, Krauss RM, Medina MW, Ritchie MD

Multivariate methods and software for association mapping in dose-response genome-wide association studies.

BioData mining

Brown CC, Havener TM, Medina MW, Krauss RM, McLeod HL, Motsinger-Reif AA

RHOA is a modulator of the cholesterol-lowering effects of statin.

PLoS genetics

Medina MW, Theusch E, Naidoo D, Bauzon F, Stevens K, Mangravite LM, Kuang YL, Krauss RM

A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT.

Pharmacogenetics and genomics

Brown CC, Havener TM, Medina MW, Auman JT, Mangravite LM, Krauss RM, McLeod HL, Motsinger-Reif AA

Effects of dietary saturated fat on LDL subclasses and apolipoprotein CIII in men.

European journal of clinical nutrition

Faghihnia N, Mangravite LM, Chiu S, Bergeron N, Krauss RM

Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment.

PloS one

Trupp M, Zhu H, Wikoff WR, Baillie RA, Zeng ZB, Karp PD, Fiehn O, Krauss RM, Kaddurah-Daouk R

Steroidogenic regulatory factor FOS is underexpressed in polycystic ovary syndrome (PCOS) adipose tissue and genetically associated with PCOS susceptibility.

The Journal of clinical endocrinology and metabolism

Jones MR, Chazenbalk G, Xu N, Chua AK, Eigler T, Mengesha E, Chen YH, Lee JM, Pall M, Li X, Chen YD, Taylor KD, Mathur R, Krauss RM, Rotter JI, Legro RS, Azziz R, Goodarzi MO

The clinical pharmacogenomics implementation consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy.

Clinical pharmacology and therapeutics

Wilke RA, Ramsey LB, Johnson SG, Maxwell WD, McLeod HL, Voora D, Krauss RM, Roden DM, Feng Q, Cooper-Dehoff RM, Gong L, Klein TE, Wadelius M, Niemi M

Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.

PloS one

Musunuru K, Romaine SP, Lettre G, Wilson JG, Volcik KA, Tsai MY, Taylor HA, Schreiner PJ, Rotter JI, Rich SS, Redline S, Psaty BM, Papanicolaou GJ, Ordovas JM, Liu K, Krauss RM, Glazer NL, Gabriel SB, Fornage M, Cupples LA, Buxbaum SG, Boerwinkle E, Ballantyne CM, Kathiresan S, Rader DJ

CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake.

PloS one

Silver HJ, Niswender KD, Keil CD, Jiang L, Feng Q, Chiu S, Krauss RM, Wilke RA

A nutrient-dense, high-fiber, fruit-based supplement bar increases HDL cholesterol, particularly large HDL, lowers homocysteine, and raises glutathione in a 2-wk trial.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Mietus-Snyder ML, Shigenaga MK, Suh JH, Shenvi SV, Lal A, McHugh T, Olson D, Lilienstein J, Krauss RM, Gildengoren G, McCann JC, Ames BN

Genetic variation in PNPLA3 but not APOC3 influences liver fat in non-alcoholic fatty liver disease.

Journal of gastroenterology and hepatology

Hyysalo J, Stojkovic I, Kotronen A, Hakkarainen A, Sevastianova K, Makkonen J, Lundbom N, Rissanen A, Krauss RM, Melander O, Orho-Melander M, Yki-Järvinen H

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

PLoS genetics

Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, Beekman M, Coassin S, Lohman K, Qi L, Kanoni S, Pankow JS, Uh HW, Wu Y, Bidulescu A, Rasmussen-Torvik LJ, Greenwood CM, Ladouceur M, Grimsby J, Manning AK, Liu CT, Kooner J, Mooser VE, Vollenweider P, Kapur KA, Chambers J, Wareham NJ, Langenberg C, Frants R, Willems-Vandijk K, Oostra BA, Willems SM, Lamina C, Winkler TW, Psaty BM, Tracy RP, Brody J, Chen I, Viikari J, Kähönen M, Pramstaller PP, Evans DM, St Pourcain B, Sattar N, Wood AR, Bandinelli S, Carlson OD, Egan JM, Böhringer S, van Heemst D, Kedenko L, Kristiansson K, Nuotio ML, Loo BM, Harris T, Garcia M, Kanaya A, Haun M, Klopp N, Wichmann HE, Deloukas P, Katsareli E, Couper DJ, Duncan BB, Kloppenburg M, Adair LS, Borja JB, Wilson JG, Musani S, Guo X, Johnson T, Semple R, Teslovich TM, Allison MA, Redline S, Buxbaum SG, Mohlke KL, Meulenbelt I, Ballantyne CM, Dedoussis GV, Hu FB, Liu Y, Paulweber B, Spector TD, Slagboom PE, Ferrucci L, Jula A, Perola M, Raitakari O, Florez JC, Salomaa V, Eriksson JG, Frayling TM, Hicks AA, Lehtimäki T, Smith GD, Siscovick DS, Kronenberg F, van Duijn C, Loos RJ, Waterworth DM, Meigs JB, Dupuis J, Richards JB, Voight BF, Scott LJ, Steinthorsdottir V, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Hofmann OM, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Boström KB, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Morris AD, Palmer CN, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Pedersen O, Barroso I, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, Soranzo N, Wheeler E, Glazer NL, Bouatia-Naji N, Mägi R, Randall J, Elliott P, Rybin D, Dehghan A, Hottenga JJ, Song K, Goel A, Lajunen T, Doney A, Cavalcanti-Proença C, Kumari M, Timpson NJ, Zabena C, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Roccasecca RM, Pattou F, Sethupathy P, Ariyurek Y, Barter P, Beilby JP, Ben-Shlomo Y, Bergmann S, Bochud M, Bonnefond A, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Crisponi L, Day IN, de Geus EJ, Delplanque J, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Grundy S, Gwilliam R, Hallmans G, Hammond N, Han X, Hartikainen AL, Hayward C, Heath SC, Hercberg S, Hillman DR, Hingorani AD, Hui J, Hung J, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Mahley R, Mangino M, Martínez-Larrad MT, McAteer JB, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Mukherjee S, Naitza S, et al

Impact of mifepristone, a glucocorticoid/progesterone antagonist, on HDL cholesterol, HDL particle concentration, and HDL function.

The Journal of clinical endocrinology and metabolism

Page ST, Krauss RM, Gross C, Ishida B, Heinecke JW, Tang C, Amory JK, Schaefer PM, Cox CJ, Kane J, Purnell JQ, Weinstein RL, Vaisar T

Structural basis of transfer between lipoproteins by cholesteryl ester transfer protein.

Nature chemical biology

Zhang L, Yan F, Zhang S, Lei D, Charles MA, Cavigiolio G, Oda M, Krauss RM, Weisgraber KH, Rye KA, Pownall HJ, Qiu X, Ren G

Changes in lipoprotein subfraction concentration and composition in healthy individuals treated with the CETP inhibitor anacetrapib.

Journal of lipid research

Krauss RM, Wojnooski K, Orr J, Geaney JC, Pinto CA, Liu Y, Wagner JA, Luk JM, Johnson-Levonas AO, Anderson MS, Dansky HM

Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts.

Journal of medical genetics

Goodarzi MO, Jones MR, Li X, Chua AK, Garcia OA, Chen YD, Krauss RM, Rotter JI, Ankener W, Legro RS, Azziz R, Strauss JF, Dunaif A, Urbanek M

Metabolic and cardiovascular genes in polycystic ovary syndrome: a candidate-wide association study (CWAS).

Steroids

Jones MR, Chua AK, Mengesha EA, Taylor KD, Chen YD, Li X, Krauss RM, Rotter JI, Legro RS, Azziz R, Goodarzi MO

Effects of the PPAR-d agonist MBX-8025 on atherogenic dyslipidemia.

Atherosclerosis

Choi YJ, Roberts BK, Wang X, Geaney JC, Naim S, Wojnoonski K, Karpf DB, Krauss RM

Changes in atherogenic dyslipidemia induced by carbohydrate restriction in men are dependent on dietary protein source.

The Journal of nutrition

Mangravite LM, Chiu S, Wojnoonski K, Rawlings RS, Bergeron N, Krauss RM

High disaccharide intake associates with atherogenic lipoprotein profile.

The British journal of nutrition

Sonestedt E, Wirfält E, Wallström P, Gullberg B, Drake I, Hlebowicz J, Nordin Fredrikson G, Hedblad B, Nilsson J, Krauss RM, Orho-Melander M

Enteric microbiome metabolites correlate with response to simvastatin treatment.

PloS one

Kaddurah-Daouk R, Baillie RA, Zhu H, Zeng ZB, Wiest MM, Nguyen UT, Wojnoonski K, Watkins SM, Trupp M, Krauss RM

Cardiovascular pharmacogenomics.

Circulation research

Roden DM, Johnson JA, Kimmel SE, Krauss RM, Medina MW, Shuldiner A, Wilke RA

MBX-8025, a novel peroxisome proliferator receptor-delta agonist: lipid and other metabolic effects in dyslipidemic overweight patients treated with and without atorvastatin.

The Journal of clinical endocrinology and metabolism

Bays HE, Schwartz S, Littlejohn T, Kerzner B, Krauss RM, Karpf DB, Choi YJ, Wang X, Naim S, Roberts BK

Harnessing expression data to identify novel candidate genes in polycystic ovary syndrome.

PloS one

Jones MR, Chua A, Chen YD, Li X, Krauss RM, Rotter JI, Legro RS, Azziz R, Goodarzi MO

Coordinately regulated alternative splicing of genes involved in cholesterol biosynthesis and uptake.

PloS one

Medina MW, Gao F, Naidoo D, Rudel LL, Temel RE, McDaniel AL, Marshall SM, Krauss RM

Energy substrate partitioning and efficiency in individuals with atherogenic lipoprotein phenotype.

Obesity (Silver Spring, Md.)

Faghihnia N, Siri-Tarino PW, Krauss RM, Brooks GA

The role of reducing intakes of saturated fat in the prevention of cardiovascular disease: where does the evidence stand in 2010?

The American journal of clinical nutrition

Astrup A, Dyerberg J, Elwood P, Hermansen K, Hu FB, Jakobsen MU, Kok FJ, Krauss RM, Lecerf JM, LeGrand P, Nestel P, Risérus U, Sanders T, Sinclair A, Stender S, Tholstrup T, Willett WC

HDL measures, particle heterogeneity, proposed nomenclature, and relation to atherosclerotic cardiovascular events.

Clinical chemistry

Rosenson RS, Brewer HB, Chapman MJ, Fazio S, Hussain MM, Kontush A, Krauss RM, Otvos JD, Remaley AT, Schaefer EJ

The emerging role of electronic medical records in pharmacogenomics.

Clinical pharmacology and therapeutics

Wilke RA, Xu H, Denny JC, Roden DM, Krauss RM, McCarty CA, Davis RL, Skaar T, Lamba J, Savova G

Saturated fatty acids and risk of coronary heart disease: modulation by replacement nutrients.

Current atherosclerosis reports

Siri-Tarino PW, Sun Q, Hu FB, Krauss RM

Changes in lipoprotein(a), oxidized phospholipids, and LDL subclasses with a low-fat high-carbohydrate diet.

Journal of lipid research

Faghihnia N, Tsimikas S, Miller ER, Witztum JL, Krauss RM

Biological, clinical and population relevance of 95 loci for blood lipids.

Nature

Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Ripatti S, Chasman DI, Willer CJ, Johansen CT, Fouchier SW, Isaacs A, Peloso GM, Barbalic M, Ricketts SL, Bis JC, Aulchenko YS, Thorleifsson G, Feitosa MF, Chambers J, Orho-Melander M, Melander O, Johnson T, Li X, Guo X, Li M, Shin Cho Y, Jin Go M, Jin Kim Y, Lee JY, Park T, Kim K, Sim X, Twee-Hee Ong R, Croteau-Chonka DC, Lange LA, Smith JD, Song K, Hua Zhao J, Yuan X, Luan J, Lamina C, Ziegler A, Zhang W, Zee RY, Wright AF, Witteman JC, Wilson JF, Willemsen G, Wichmann HE, Whitfield JB, Waterworth DM, Wareham NJ, Waeber G, Vollenweider P, Voight BF, Vitart V, Uitterlinden AG, Uda M, Tuomilehto J, Thompson JR, Tanaka T, Surakka I, Stringham HM, Spector TD, Soranzo N, Smit JH, Sinisalo J, Silander K, Sijbrands EJ, Scuteri A, Scott J, Schlessinger D, Sanna S, Salomaa V, Saharinen J, Sabatti C, Ruokonen A, Rudan I, Rose LM, Roberts R, Rieder M, Psaty BM, Pramstaller PP, Pichler I, Perola M, Penninx BW, Pedersen NL, Pattaro C, Parker AN, Pare G, Oostra BA, O'Donnell CJ, Nieminen MS, Nickerson DA, Montgomery GW, Meitinger T, McPherson R, McCarthy MI, McArdle W, Masson D, Martin NG, Marroni F, Mangino M, Magnusson PK, Lucas G, Luben R, Loos RJ, Lokki ML, Lettre G, Langenberg C, Launer LJ, Lakatta EG, Laaksonen R, Kyvik KO, Kronenberg F, König IR, Khaw KT, Kaprio J, Kaplan LM, Johansson A, Jarvelin MR, Janssens AC, Ingelsson E, Igl W, Kees Hovingh G, Hottenga JJ, Hofman A, Hicks AA, Hengstenberg C, Heid IM, Hayward C, Havulinna AS, Hastie ND, Harris TB, Haritunians T, Hall AS, Gyllensten U, Guiducci C, Groop LC, Gonzalez E, Gieger C, Freimer NB, Ferrucci L, Erdmann J, Elliott P, Ejebe KG, Döring A, Dominiczak AF, Demissie S, Deloukas P, de Geus EJ, de Faire U, Crawford G, Collins FS, Chen YD, Caulfield MJ, Campbell H, Burtt NP, Bonnycastle LL, Boomsma DI, Boekholdt SM, Bergman RN, Barroso I, Bandinelli S, Ballantyne CM, Assimes TL, Quertermous T, Altshuler D, Seielstad M, Wong TY, Tai ES, Feranil AB, Kuzawa CW, Adair LS, Taylor HA, Borecki IB, Gabriel SB, Wilson JG, Holm H, Thorsteinsdottir U, Gudnason V, Krauss RM, Mohlke KL, Ordovas JM, Munroe PB, Kooner JS, Tall AR, Hegele RA, Kastelein JJ, Schadt EE, Rotter JI, Boerwinkle E, Strachan DP, Mooser V, Stefansson K, Reilly MP, Samani NJ, Schunkert H, Cupples LA, Sandhu MS, Ridker PM, Rader DJ, van Duijn CM, Peltonen L, Abecasis GR, Boehnke M, Kathiresan S

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus.

Nature

Musunuru K, Strong A, Frank-Kamenetsky M, Lee NE, Ahfeldt T, Sachs KV, Li X, Li H, Kuperwasser N, Ruda VM, Pirruccello JP, Muchmore B, Prokunina-Olsson L, Hall JL, Schadt EE, Morales CR, Lund-Katz S, Phillips MC, Wong J, Cantley W, Racie T, Ejebe KG, Orho-Melander M, Melander O, Koteliansky V, Fitzgerald K, Krauss RM, Cowan CA, Kathiresan S, Rader DJ

Lipoprotein subfractions and cardiovascular disease risk.

Current opinion in lipidology

Krauss RM

Reversal of small, dense LDL subclass phenotype by weight loss is associated with impaired fat oxidation.

Obesity (Silver Spring, Md.)

Siri-Tarino PW, Woods AC, Bray GA, Krauss RM

VLDL hydrolysis by LPL activates PPAR-alpha through generation of unbound fatty acids.

Journal of lipid research

Ruby MA, Goldenson B, Orasanu G, Johnston TP, Plutzky J, Krauss RM

Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin.

Arteriosclerosis, thrombosis, and vascular biology

Mangravite LM, Medina MW, Cui J, Pressman S, Smith JD, Rieder MJ, Guo X, Nickerson DA, Rotter JI, Krauss RM

Lipidomic analysis of variation in response to simvastatin in the Cholesterol and Pharmacogenetics Study.

Metabolomics : Official journal of the Metabolomic Society

Kaddurah-Daouk R, Baillie RA, Zhu H, Zeng ZB, Wiest MM, Nguyen UT, Watkins SM, Krauss RM

Genome-wide association of lipid-lowering response to statins in combined study populations.

PloS one

Barber MJ, Mangravite LM, Hyde CL, Chasman DI, Smith JD, McCarty CA, Li X, Wilke RA, Rieder MJ, Williams PT, Ridker PM, Chatterjee A, Rotter JI, Nickerson DA, Stephens M, Krauss RM

Plasma triglyceride concentrations are rapidly reduced following individual bouts of endurance exercise in women.

European journal of applied physiology

Henderson GC, Krauss RM, Fattor JA, Faghihnia N, Luke-Zeitoun M, Brooks GA

Saturated fat, carbohydrate, and cardiovascular disease.

The American journal of clinical nutrition

Siri-Tarino PW, Sun Q, Hu FB, Krauss RM

Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease.

The American journal of clinical nutrition

Siri-Tarino PW, Sun Q, Hu FB, Krauss RM

A gene score of nine LDL and HDL regulating genes is associated with fluvastatin-induced cholesterol changes in women.

Journal of lipid research

Hamrefors V, Orho-Melander M, Krauss RM, Hedblad B, Almgren P, Berglund G, Melander O

Ion mobility analysis of lipoprotein subfractions identifies three independent axes of cardiovascular risk.

Arteriosclerosis, thrombosis, and vascular biology

Musunuru K, Orho-Melander M, Caulfield MP, Li S, Salameh WA, Reitz RE, Berglund G, Hedblad B, Engström G, Williams PT, Kathiresan S, Melander O, Krauss RM

The role of HMGCR alternative splicing in statin efficacy.

Trends in cardiovascular medicine

Medina MW, Krauss RM

Reversal of small, dense LDL subclass phenotype by normalization of adiposity.

Obesity (Silver Spring, Md.)

Siri-Tarino PW, Williams PT, Fernstrom HS, Rawlings RS, Krauss RM

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans.

The Journal of clinical investigation

Stanhope KL, Schwarz JM, Keim NL, Griffen SC, Bremer AA, Graham JL, Hatcher B, Cox CL, Dyachenko A, Zhang W, McGahan JP, Seibert A, Krauss RM, Chiu S, Schaefer EJ, Ai M, Otokozawa S, Nakajima K, Nakano T, Beysen C, Hellerstein MK, Berglund L, Havel PJ

Hepatic nuclear factor 1-alpha: inflammation, genetics, and atherosclerosis.

Current opinion in lipidology

Armendariz AD, Krauss RM

A reappraisal of the impact of dairy foods and milk fat on cardiovascular disease risk.

European journal of nutrition

German JB, Gibson RA, Krauss RM, Nestel P, Lamarche B, van Staveren WA, Steijns JM, de Groot LC, Lock AL, Destaillats F

Population analysis of large copy number variants and hotspots of human genetic disease.

American journal of human genetics

Itsara A, Cooper GM, Baker C, Girirajan S, Li J, Absher D, Krauss RM, Myers RM, Ridker PM, Chasman DI, Mefford H, Ying P, Nickerson DA, Eichler EE

Use of an electronic medical record to characterize cases of intermediate statin-induced muscle toxicity.

Preventive cardiology

Mareedu RK, Modhia FM, Kanin EI, Linneman JG, Kitchner T, McCarty CA, Krauss RM, Wilke RA

Pharmacogenomics of statin response.

Current opinion in molecular therapeutics

Mangravite LM, Wilke RA, Zhang J, Krauss RM

Consumption of fructose-sweetened beverages for 10 weeks increases postprandial triacylglycerol and apolipoprotein-B concentrations in overweight and obese women.

The British journal of nutrition

Swarbrick MM, Stanhope KL, Elliott SS, Graham JL, Krauss RM, Christiansen MP, Griffen SC, Keim NL, Havel PJ

Characterization of low-density lipoprotein cholesterol-lowering efficacy for atorvastatin in a population-based DNA biorepository.

Basic & clinical pharmacology & toxicology

Wilke RA, Berg RL, Linneman JG, Zhao C, McCarty CA, Krauss RM

Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication.

Circulation. Cardiovascular genetics

Chasman DI, Paré G, Zee RY, Parker AN, Cook NR, Buring JE, Kwiatkowski DJ, Rose LM, Smith JD, Williams PT, Rieder MJ, Rotter JI, Nickerson DA, Krauss RM, Miletich JP, Ridker PM

Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins.

Proceedings of the National Academy of Sciences of the United States of America

Ruby MA, Nomura DK, Hudak CS, Mangravite LM, Chiu S, Casida JE, Krauss RM

Interview.

Pharmacogenomics

Krauss RM

Tracing sub-structure in the European American population with PCA-informative markers.

PLoS genetics

Paschou P, Drineas P, Lewis J, Nievergelt CM, Nickerson DA, Smith JD, Ridker PM, Chasman DI, Krauss RM, Ziv E

A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma.

Journal of lipid research

Bergmark C, Dewan A, Orsoni A, Merki E, Miller ER, Shin MJ, Binder CJ, Hörkkö S, Krauss RM, Chapman MJ, Witztum JL, Tsimikas S

Direct determination of lipoprotein particle sizes and concentrations by ion mobility analysis.

Clinical chemistry

Caulfield MP, Li S, Lee G, Blanche PJ, Salameh WA, Benner WH, Reitz RE, Krauss RM

Protein in optimal health: heart disease and type 2 diabetes.

The American journal of clinical nutrition

Layman DK, Clifton P, Gannon MC, Krauss RM, Nuttall FQ

Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.

American journal of human genetics

Reiner AP, Barber MJ, Guan Y, Ridker PM, Lange LA, Chasman DI, Walston JD, Cooper GM, Jenny NS, Rieder MJ, Durda JP, Smith JD, Novembre J, Tracy RP, Rotter JI, Stephens M, Nickerson DA, Krauss RM

Lipid metabolism in children and adolescents: Impact on vascular biology.

Journal of clinical lipidology

Mietus-Snyder M, Krauss RM

The editor's roundtable: expanded versus standard lipid panels in assessing and managing cardiovascular risk.

The American journal of cardiology

Sulkes D, Brown BG, Krauss RM, Segrest JP, Sniderman AD, Roberts WC

Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment.

Circulation

Krauss RM, Mangravite LM, Smith JD, Medina MW, Wang D, Guo X, Rieder MJ, Simon JA, Hulley SB, Waters D, Saad M, Williams PT, Taylor KD, Yang H, Nickerson DA, Rotter JI

Analysis of polymorphisms in the 3' untranslated region of the LDL receptor gene and their effect on plasma cholesterol levels and drug response.

International journal of molecular medicine

Chen W, Wang S, Ma Y, Zhou Y, Liu H, Strnad P, Kraemer FB, Krauss RM, Liu J

What can the genome tell us about LDL cholesterol?

Lancet (London, England)

Krauss RM

Atherogenic lipid phenotype in a general group of subjects.

Archives of pathology & laboratory medicine

Van J, Pan J, Charles MA, Krauss R, Wong N, Wu X

Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges.

Nature reviews. Drug discovery

Wilke RA, Lin DW, Roden DM, Watkins PB, Flockhart D, Zineh I, Giacomini KM, Krauss RM

Estrogen receptor genotypes, menopausal status, and the lipid effects of tamoxifen.

Clinical pharmacology and therapeutics

Ntukidem NI, Nguyen AT, Stearns V, Rehman M, Schott A, Skaar T, Jin Y, Blanche P, Li L, Lemler S, Hayden J, Krauss RM, Desta Z, Flockhart DA, Hayes DF

Differential effects of ramipril on ambulatory blood pressure in African Americans and Caucasians.

American journal of hypertension

Moran A, Simon JA, Shiboski S, Pickering TG, Waters D, Rotter JI, Lyon C, Nickerson D, Yang H, Saad M, Hsueh W, Krauss RM

Pharmacogenomics of statin response.

Current opinion in lipidology

Mangravite LM, Krauss RM

Genetic nondiscrimination legislation: a critical prerequisite for pharmacogenomics data sharing.

Pharmacogenomics

Altman RB, Benowitz N, Gurwitz D, Lunshof J, Relling M, Lamba J, Wieben E, Mooney S, Giacomini K, Weiss S, Johnson JA, McLeod H, Flockhart D, Weinshilboum R, Shuldiner AR, Roden D, Krauss RM, Ratain M

When good drugs go bad.

Nature

Giacomini KM, Krauss RM, Roden DM, Eichelbaum M, Hayden MR, Nakamura Y

The pharmacogenetics research network: from SNP discovery to clinical drug response.

Clinical pharmacology and therapeutics

Giacomini KM, Brett CM, Altman RB, Benowitz NL, Dolan ME, Flockhart DA, Johnson JA, Hayes DF, Klein T, Krauss RM, Kroetz DL, McLeod HL, Nguyen AT, Ratain MJ, Relling MV, Reus V, Roden DM, Schaefer CA, Shuldiner AR, Skaar T, Tantisira K, Tyndale RF, Wang L, Weinshilboum RM, Weiss ST, Zineh I

Association between angiotensinogen, angiotensin II receptor genes, and blood pressure response to an angiotensin-converting enzyme inhibitor.

Circulation

Su X, Lee L, Li X, Lv J, Hu Y, Zhan S, Cao W, Mei L, Tang YM, Wang D, Krauss RM, Taylor KD, Rotter JI, Yang H

Pharmacogenomics: challenges and opportunities.

Annals of internal medicine

Roden DM, Altman RB, Benowitz NL, Flockhart DA, Giacomini KM, Johnson JA, Krauss RM, McLeod HL, Ratain MJ, Relling MV, Ring HZ, Shuldiner AR, Weinshilboum RM, Weiss ST

Endurance training has little effect on active muscle free fatty acid, lipoprotein cholesterol, or triglyceride net balances.

American journal of physiology. Endocrinology and metabolism

Jacobs KA, Krauss RM, Fattor JA, Horning MA, Friedlander AL, Bauer TA, Hagobian TA, Wolfel EE, Brooks GA

Separate effects of reduced carbohydrate intake and weight loss on atherogenic dyslipidemia.

The American journal of clinical nutrition

Krauss RM, Blanche PJ, Rawlings RS, Fernstrom HS, Williams PT

Clinical implications of pharmacogenomics of statin treatment.

The pharmacogenomics journal

Mangravite LM, Thorn CF, Krauss RM

Apo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: report of the thirty-person/ten-country panel.

Journal of internal medicine

Barter PJ, Ballantyne CM, Carmena R, Castro Cabezas M, Chapman MJ, Couture P, de Graaf J, Durrington PN, Faergeman O, Frohlich J, Furberg CD, Gagne C, Haffner SM, Humphries SE, Jungner I, Krauss RM, Kwiterovich P, Marcovina S, Packard CJ, Pearson TA, Reddy KS, Rosenson R, Sarrafzadegan N, Sniderman AD, Stalenhoef AF, Stein E, Talmud PJ, Tonkin AM, Walldius G, Williams KM

Phenotypic predictors of response to simvastatin therapy among African-Americans and Caucasians: the Cholesterol and Pharmacogenetics (CAP) Study.

The American journal of cardiology

Simon JA, Lin F, Hulley SB, Blanche PJ, Waters D, Shiboski S, Rotter JI, Nickerson DA, Yang H, Saad M, Krauss RM

Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement.

Current opinion in cardiology

Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC, Spertus JA, Costa F

Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement: Executive Summary.

Critical pathways in cardiology

Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC, Spertus JA

Managing abnormal blood lipids: a collaborative approach.

Circulation

Fletcher B, Berra K, Ades P, Braun LT, Burke LE, Durstine JL, Fair JM, Fletcher GF, Goff D, Hayman LL, Hiatt WR, Miller NH, Krauss R, Kris-Etherton P, Stone N, Wilterdink J, Winston M

Diagnosis and management of the metabolic syndrome. An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Executive summary.

Cardiology in review

Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC, Spertus JA, Costa F

The case for strategic international alliances to harness nutritional genomics for public and personal health.

The British journal of nutrition

Kaput J, Ordovas JM, Ferguson L, van Ommen B, Rodriguez RL, Allen L, Ames BN, Dawson K, German B, Krauss R, Malyj W, Archer MC, Barnes S, Bartholomew A, Birk R, van Bladeren P, Bradford KJ, Brown KH, Caetano R, Castle D, Chadwick R, Clarke S, Clément K, Cooney CA, Corella D, Manica da Cruz IB, Daniel H, Duster T, Ebbesson SO, Elliott R, Fairweather-Tait S, Felton J, Fenech M, Finley JW, Fogg-Johnson N, Gill-Garrison R, Gibney MJ, Gillies PJ, Gustafsson JA, Hartman JL, He L, Hwang JK, Jais JP, Jang Y, Joost H, Junien C, Kanter M, Kibbe WA, Koletzko B, Korf BR, Kornman K, Krempin DW, Langin D, Lauren DR, Ho Lee J, Leveille GA, Lin SJ, Mathers J, Mayne M, McNabb W, Milner JA, Morgan P, Muller M, Nikolsky Y, van der Ouderaa F, Park T, Pensel N, Perez-Jimenez F, Poutanen K, Roberts M, Saris WH, Schuster G, Shelling AN, Simopoulos AP, Southon S, Tai ES, Towne B, Trayhurn P, Uauy R, Visek WJ, Warden C, Weiss R, Wiencke J, Winkler J, Wolff GL, Zhao-Wilson X, Zucker JD

Dietary and genetic probes of atherogenic dyslipidemia.

Arteriosclerosis, thrombosis, and vascular biology

Krauss RM

Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement.

Circulation

Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC, Spertus JA, Costa F

Is there a simple way to identify insulin-resistant individuals at increased risk of cardiovascular disease?

The American journal of cardiology

McLaughlin T, Reaven G, Abbasi F, Lamendola C, Saad M, Waters D, Simon J, Krauss RM

Concordant lipoprotein and weight responses to dietary fat change in identical twins with divergent exercise levels 1.

The American journal of clinical nutrition

Williams PT, Blanche PJ, Rawlings R, Krauss RM

Role of CYP27A in cholesterol and bile acid metabolism.

Journal of lipid research

Dubrac S, Lear SR, Ananthanarayanan M, Balasubramaniyan N, Bollineni J, Shefer S, Hyogo H, Cohen DE, Blanche PJ, Krauss RM, Batta AK, Salen G, Suchy FJ, Maeda N, Erickson SK

Low-density lipoprotein particle size loci in familial combined hyperlipidemia: evidence for multiple loci from a genome scan.

Arteriosclerosis, thrombosis, and vascular biology

Badzioch MD, Igo RP, Gagnon F, Brunzell JD, Krauss RM, Motulsky AG, Wijsman EM, Jarvik GP

Dyslipidemia in type 2 diabetes.

The Medical clinics of North America

Krauss RM, Siri PW

Metabolic abnormalities: triglyceride and low-density lipoprotein.

Endocrinology and metabolism clinics of North America

Krauss RM, Siri PW

Hold the antioxidants and improve plasma lipids?

The Journal of clinical investigation

Krauss RM

Plasma clearance of human low-density lipoprotein in human apolipoprotein B transgenic mice is related to particle diameter.

Metabolism: clinical and experimental

Berneis K, Shames DM, Blanche PJ, La Belle M, Rizzo M, Krauss RM

Haplotypes in the APOA1-C3-A4-A5 gene cluster affect plasma lipids in both humans and baboons.

Human molecular genetics

Wang QF, Liu X, O'Connell J, Peng Z, Krauss RM, Rainwater DL, VandeBerg JL, Rubin EM, Cheng JF, Pennacchio LA

Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults.

Proceedings of the National Academy of Sciences of the United States of America

Licinio J, Caglayan S, Ozata M, Yildiz BO, de Miranda PB, O'Kirwan F, Whitby R, Liang L, Cohen P, Bhasin S, Krauss RM, Veldhuis JD, Wagner AJ, DePaoli AM, McCann SM, Wong ML

Association of the APOLIPOPROTEIN A1/C3/A4/A5 gene cluster with triglyceride levels and LDL particle size in familial combined hyperlipidemia.

Circulation research

Mar R, Pajukanta P, Allayee H, Groenendijk M, Dallinga-Thie G, Krauss RM, Sinsheimer JS, Cantor RM, de Bruin TW, Lusis AJ

Obesity in BSB mice is correlated with expression of genes for iron homeostasis and leptin.

Obesity research

Farahani P, Chiu S, Bowlus CL, Boffelli D, Lee E, Fisler JS, Krauss RM, Warden CH

Subclasses of low-density lipoprotein and very low-density lipoprotein in familial combined hyperlipidemia: relationship to multiple lipoprotein phenotype.

Arteriosclerosis, thrombosis, and vascular biology

Georgieva AM, van Greevenbroek MM, Krauss RM, Brouwers MC, Vermeulen VM, Robertus-Teunissen MG, van der Kallen CJ, de Bruin TW

Effects on lipoprotein subclasses of combined expression of human hepatic lipase and human apoB in transgenic rabbits.

Arteriosclerosis, thrombosis, and vascular biology

Rizzo M, Taylor JM, Barbagallo CM, Berneis K, Blanche PJ, Krauss RM

Insulin resistance syndrome and dyslipidemia.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists

Krauss RM

Determination and use of haplotypes: ethnic comparison and association of the lipoprotein lipase gene and coronary artery disease in Mexican-Americans.

Genetics in medicine : official journal of the American College of Medical Genetics

Goodarzi MO, Guo X, Taylor KD, Quiñones MJ, Samayoa C, Yang H, Saad MF, Palotie A, Krauss RM, Hsueh WA, Rotter JI

American College of Endocrinology position statement on the insulin resistance syndrome.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists

Einhorn D, Reaven GM, Cobin RH, Ford E, Ganda OP, Handelsman Y, Hellman R, Jellinger PS, Kendall D, Krauss RM, Neufeld ND, Petak SM, Rodbard HW, Seibel JA, Smith DA, Wilson PW

Smallest LDL particles are most strongly related to coronary disease progression in men.

Arteriosclerosis, thrombosis, and vascular biology

Williams PT, Superko HR, Haskell WL, Alderman EL, Blanche PJ, Holl LG, Krauss RM

Effects of simvastatin, an HMG-CoA reductase inhibitor, in patients with hypertriglyceridemia.

Clinical cardiology

Isaacsohn J, Hunninghake D, Schrott H, Dujovne CA, Knopp R, Weiss SR, Bays H, Crouse JR, Davidson MH, Keilson LM, McKenney J, Korenman SG, Dobs AS, Stein E, Krauss RM, Maccubbin D, Cho M, Plotkin DJ, Mitchel YB

Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels.

Human molecular genetics

Pennacchio LA, Olivier M, Hubacek JA, Krauss RM, Rubin EM, Cohen JC

ApoC-III content of apoB-containing lipoproteins is associated with binding to the vascular proteoglycan biglycan.

Journal of lipid research

Olin-Lewis K, Krauss RM, La Belle M, Blanche PJ, Barrett PH, Wight TN, Chait A

Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia.

Journal of lipid research

Attie AD, Krauss RM, Gray-Keller MP, Brownlie A, Miyazaki M, Kastelein JJ, Lusis AJ, Stalenhoef AF, Stoehr JP, Hayden MR, Ntambi JM

Metabolic origins and clinical significance of LDL heterogeneity.

Journal of lipid research

Berneis KK, Krauss RM

Metabolic effects of nandrolone decanoate and resistance training in men with HIV.

American journal of physiology. Endocrinology and metabolism

Sattler FR, Schroeder ET, Dube MP, Jaque SV, Martinez C, Blanche PJ, Azen S, Krauss RM

Analysis and quantitation of biotinylated apoB-containing lipoproteins with streptavidin-Cy3.

Journal of lipid research

Berneis K, La Belle M, Blanche PJ, Krauss RM

Individualized hormone-replacement therapy?

The New England journal of medicine

Krauss RM

Altered activities of anti-atherogenic enzymes LCAT, paraoxonase, and platelet-activating factor acetylhydrolase in atherosclerosis-susceptible mice.

Journal of lipid research

Forte TM, Subbanagounder G, Berliner JA, Blanche PJ, Clermont AO, Jia Z, Oda MN, Krauss RM, Bielicki JK

Properties of triglyceride-rich and cholesterol-rich lipoproteins in the remnant-like particle fraction of human blood plasma.

Journal of lipid research

Campos E, Kotite L, Blanche P, Mitsugi Y, Frost PH, Masharani U, Krauss RM, Havel RJ

AHA/ACC Guidelines for Preventing Heart Attack and Death in Patients With Atherosclerotic Cardiovascular Disease: 2001 update. A statement for healthcare professionals from the American Heart Association and the American College of Cardiology.

Journal of the American College of Cardiology

Smith SC, Blair SN, Bonow RO, Brass LM, Cerqueira MD, Dracup K, Fuster V, Gotto A, Grundy SM, Miller NH, Jacobs A, Jones D, Krauss RM, Mosca L, Ockene I, Pasternak RC, Pearson T, Pfeffer MA, Starke RD, Taubert KA

An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing.

Science (New York, N.Y.)

Pennacchio LA, Olivier M, Hubacek JA, Cohen JC, Cox DR, Fruchart JC, Krauss RM, Rubin EM

AHA/ACC Scientific Statement: AHA/ACC guidelines for preventing heart attack and death in patients with atherosclerotic cardiovascular disease: 2001 update: A statement for healthcare professionals from the American Heart Association and the American Coll

Circulation

Smith SC, Blair SN, Bonow RO, Brass LM, Cerqueira MD, Dracup K, Fuster V, Gotto A, Grundy SM, Miller NH, Jacobs A, Jones D, Krauss RM, Mosca L, Ockene I, Pasternak RC, Pearson T, Pfeffer MA, Starke RD, Taubert KA

AHA scientific statement: summary of the Scientific Conference on Dietary Fatty Acids and Cardiovascular Health. Conference summary from the Nutrition Committee of the American Heart Association.

The Journal of nutrition

Kris-Etherton P, Daniels SR, Eckel RH, Engler M, Howard BV, Krauss RM, Lichtenstein AH, Sacks F, St Jeor S, Stampfer M, Grundy SM, Appel LJ, Byers T, Campos H, Cooney G, Denke MA, Kennedy E, Marckmann P, Pearson TA, Riccardi G, Rudel LL, Rudrum M, Stein DT, Tracy RP, Ursin V, Vogel RA, Zock PL, Bazzarre TL, Clark J

Familial factors in the antihypertensive response to lisinopril.

American journal of hypertension

Hollenberg NK, Anzalone DA, Falkner B, Fisher ND, Hopkins PN, Hsueh W, Hutchinson H, Krauss RM, Price DA, Raskin P, Reaven GM

Summary of the scientific conference on dietary fatty acids and cardiovascular health: conference summary from the nutrition committee of the American Heart Association.

Circulation

Kris-Etherton P, Daniels SR, Eckel RH, Engler M, Howard BV, Krauss RM, Lichtenstein AH, Sacks F, St Jeor S, Stampfer M, Eckel RH, Grundy SM, Appel LJ, Byers T, Campos H, Cooney G, Denke MA, Howard BV, Kennedy E, Krauss RM, Kris-Etherton P, Lichtenstein AH, Marckmann P, Pearson TA, Riccardi G, Rudel LL, Rudrum M, Sacks F, Stein DT, Tracy RP, Ursin V, Vogel RA, Zock PL, Bazzarre TL, Clark J

Enhanced oxidative susceptibility and reduced antioxidant content of metabolic precursors of small, dense low-density lipoproteins.

The American journal of medicine

Tribble DL, Rizzo M, Chait A, Lewis DM, Blanche PJ, Krauss RM

Lipoprotein candidate genes for multivariate factors of the insulin resistance syndrome: a sib-pair linkage analysis in women twins.

Twin research : the official journal of the International Society for Twin Studies

Edwards KL, Talmud PJ, Newman B, Krauss RM, Austin MA

Dietary and genetic effects on LDL heterogeneity.

World review of nutrition and dietetics

Krauss RM

Revision 2000: a statement for healthcare professionals from the Nutrition Committee of the American Heart Association.

The Journal of nutrition

Krauss RM, Eckel RH, Howard B, Appel LJ, Daniels SR, Deckelbaum RJ, Erdman JW, Kris-Etherton P, Goldberg IJ, Kotchen TA, Lichtenstein AH, Mitch WE, Mullis R, Robinson K, Wylie-Rosett J, St Jeor S, Suttie J, Tribble DL, Bazzarre TL

AHA Dietary Guidelines: revision 2000: A statement for healthcare professionals from the Nutrition Committee of the American Heart Association.

Stroke

Krauss RM, Eckel RH, Howard B, Appel LJ, Daniels SR, Deckelbaum RJ, Erdman JW, Kris-Etherton P, Goldberg IJ, Kotchen TA, Lichtenstein AH, Mitch WE, Mullis R, Robinson K, Wylie-Rosett J, St Jeor S, Suttie J, Tribble DL, Bazzarre TL

AHA Dietary Guidelines: revision 2000: A statement for healthcare professionals from the Nutrition Committee of the American Heart Association.

Circulation

Krauss RM, Eckel RH, Howard B, Appel LJ, Daniels SR, Deckelbaum RJ, Erdman JW, Kris-Etherton P, Goldberg IJ, Kotchen TA, Lichtenstein AH, Mitch WE, Mullis R, Robinson K, Wylie-Rosett J, St Jeor S, Suttie J, Tribble DL, Bazzarre TL

Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9.

Science (New York, N.Y.)

López-Coviella I, Berse B, Krauss R, Thies RS, Blusztajn JK

Cardiovascular fitness, body composition, and lipoprotein lipid metabolism in older men.

The journals of gerontology. Series A, Biological sciences and medical sciences

Goldberg AP, Busby-Whitehead MJ, Katzel LI, Krauss RM, Lumpkin M, Hagberg JM

Reduced LDL particle size in children consuming a very-low-fat diet is related to parental LDL-subclass patterns.

The American journal of clinical nutrition

Dreon DM, Fernstrom HA, Williams PT, Krauss RM

Genetic recipes for heart-healthy diets.

The American journal of clinical nutrition

Krauss RM

Contribution of the hepatic lipase gene to the atherogenic lipoprotein phenotype in familial combined hyperlipidemia.

Journal of lipid research

Allayee H, Dominguez KM, Aouizerat BE, Krauss RM, Rotter JI, Lu J, Cantor RM, de Bruin TW, Lusis AJ

Genomic interval engineering of mice identifies a novel modulator of triglyceride production.

Proceedings of the National Academy of Sciences of the United States of America

Zhu Y, Jong MC, Frazer KA, Gong E, Krauss RM, Cheng JF, Boffelli D, Rubin EM

Prevention Conference V: Beyond secondary prevention: identifying the high-risk patient for primary prevention: medical office assessment: Writing Group I.

Circulation

Grundy SM, Bazzarre T, Cleeman J, D'Agostino RB, Hill M, Houston-Miller N, Kannel WB, Krauss R, Krumholz HM, Lauer RM, Ockene IS, Pasternak RC, Pearson T, Ridker PM, Wood D

Low-fat diets, lipoprotein subclasses, and heart disease risk.

The American journal of clinical nutrition

Williams PT, Krauss RM

Effects of a low-fat, high-carbohydrate diet on VLDL-triglyceride assembly, production, and clearance.

The Journal of clinical investigation

Parks EJ, Krauss RM, Christiansen MP, Neese RA, Hellerstein MK

Structural heterogeneity of apoB-containing serum lipoproteins visualized using cryo-electron microscopy.

Journal of lipid research

van Antwerpen R, La Belle M, Navratilova E, Krauss RM

Pathophysiology of triglyceride-rich lipoproteins in atherothrombosis: clinical aspects.

Clinical cardiology

Hodis HN, Mack WJ, Krauss RM, Alaupovic P

A very low-fat diet is not associated with improved lipoprotein profiles in men with a predominance of large, low-density lipoproteins.

The American journal of clinical nutrition

Dreon DM, Fernstrom HA, Williams PT, Krauss RM

Overexpression of human hepatic lipase and ApoE in transgenic rabbits attenuates response to dietary cholesterol and alters lipoprotein subclass distributions.

Arteriosclerosis, thrombosis, and vascular biology

Barbagallo CM, Fan J, Blanche PJ, Rizzo M, Taylor JM, Krauss RM

Lamellar lipoproteins uniquely contribute to hyperlipidemia in mice doubly deficient in apolipoprotein E and hepatic lipase.

Proceedings of the National Academy of Sciences of the United States of America

Bergeron N, Kotite L, Verges M, Blanche P, Hamilton RL, Krauss RM, Bensadoun A, Havel RJ

Obesity: impact of cardiovascular disease.

Circulation

Krauss RM, Winston M, Fletcher RN, Grundy SM

Relationships between insulin resistance and lipoproteins in nondiabetic African Americans, Hispanics, and non-Hispanic whites: the Insulin Resistance Atherosclerosis Study.

Metabolism: clinical and experimental

Howard BV, Mayer-Davis EJ, Goff D, Zaccaro DJ, Laws A, Robbins DC, Saad MF, Selby J, Hamman RF, Krauss RM, Haffner SM

Families with familial combined hyperlipidemia and families enriched for coronary artery disease share genetic determinants for the atherogenic lipoprotein phenotype.

American journal of human genetics

Allayee H, Aouizerat BE, Cantor RM, Dallinga-Thie GM, Krauss RM, Lanning CD, Rotter JI, Lusis AJ, de Bruin TW

Metabolism of lipoproteins containing apolipoprotein B in hepatic lipase-deficient mice.

Journal of lipid research

Qiu S, Bergeron N, Kotite L, Krauss RM, Bensadoun A, Havel RJ

The American College of Physicians guidelines for screening blood cholesterol levels: a commentary.

The American journal of medicine

Criqui MH, Kinosian B, Glick H, Deedwania PC, Krauss RM

Sulfur K-edge x-ray absorption spectroscopy: a spectroscopic tool to examine the redox state of S-containing metabolites in vivo.

Proceedings of the National Academy of Sciences of the United States of America

Rompel A, Cinco RM, Latimer MJ, McDermott AE, Guiles RD, Quintanilha A, Krauss RM, Sauer K, Yachandra VK, Klein MP

Change in dietary saturated fat intake is correlated with change in mass of large low-density-lipoprotein particles in men.

The American journal of clinical nutrition

Dreon DM, Fernstrom HA, Campos H, Blanche P, Williams PT, Krauss RM

The obesity problem.

The New England journal of medicine

Krauss RM, Eckel RH

Influence of apoE content on receptor binding of large, bouyant LDL in subjects with different LDL subclass phenotypes.

Arteriosclerosis, thrombosis, and vascular biology

Barbagallo CM, Levine GA, Blanche PJ, Ishida BY, Krauss RM

Atherogenicity of triglyceride-rich lipoproteins.

The American journal of cardiology

Krauss RM

Candidate-gene studies of the atherogenic lipoprotein phenotype: a sib-pair linkage analysis of DZ women twins.

American journal of human genetics

Austin MA, Talmud PJ, Luong LA, Haddad L, Day IN, Newman B, Edwards KL, Krauss RM, Humphries SE

Quantification of HDL2 and HDL3 cholesterol by the Vertical Auto Profile-II (VAP-II) methodology.

Journal of lipid research

Kulkarni KR, Marcovina SM, Krauss RM, Garber DW, Glasscock AM, Segrest JP

Relation of LDL size to the insulin resistance syndrome and coronary heart disease in American Indians. The Strong Heart Study.

Arteriosclerosis, thrombosis, and vascular biology

Gray RS, Robbins DC, Wang W, Yeh JL, Fabsitz RR, Cowan LD, Welty TK, Lee ET, Krauss RM, Howard BV

Diet-gene interactions in human lipoprotein metabolism.

Journal of the American College of Nutrition

Dreon DM, Krauss RM

Effect of fluvastatin on low-density lipoprotein peak particle diameter.

The American journal of cardiology

Superko HR, Krauss RM, DiRicco C

Associations of age, adiposity, menopause, and alcohol intake with low-density lipoprotein subclasses.

Arteriosclerosis, thrombosis, and vascular biology

Williams PT, Krauss RM

Intermediate-density lipoproteins and progression of carotid arterial wall intima-media thickness.

Circulation

Hodis HN, Mack WJ, Dunn M, Liu C, Liu C, Selzer RH, Krauss RM

Charge properties of low density lipoprotein subclasses.

Journal of lipid research

La Belle M, Blanche PJ, Krauss RM

Cryo-electron microscopy of low density lipoprotein and reconstituted discoidal high density lipoprotein: imaging of the apolipoprotein moiety.

Journal of lipid research

van Antwerpen R, Chen GC, Pullinger CR, Kane JP, LaBelle M, Krauss RM, Luna-Chavez C, Forte TM, Gilkey JC

LDL subclass patterns and lipoprotein response to a low-fat, high-carbohydrate diet in women.

Arteriosclerosis, thrombosis, and vascular biology

Dreon DM, Fernstrom HA, Williams PT, Krauss RM

Variability of plasma HDL subclass concentrations in men and women over time.

Arteriosclerosis, thrombosis, and vascular biology

Williams PT, Dreon DM, Blanche PJ, Krauss RM

Understanding the basis for variation in response to cholesterol-lowering diets.

The American journal of clinical nutrition

Krauss RM

Heritability of factors of the insulin resistance syndrome in women twins.

Genetic epidemiology

Edwards KL, Newman B, Mayer E, Selby JV, Krauss RM, Austin MA

Selective resistance of LDL core lipids to iron-mediated oxidation. Implications for the biological properties of iron-oxidized LDL.

Arteriosclerosis, thrombosis, and vascular biology

Tribble DL, Chu BM, Levine GA, Krauss RM, Gong EL

Dietary sodium and blood pressure.

JAMA

Kotchen TA, Krauss RM

Dietary guidelines for healthy American adults. A statement for health professionals from the Nutrition Committee, American Heart Association.

Circulation

Krauss RM, Deckelbaum RJ, Ernst N, Fisher E, Howard BV, Knopp RH, Kotchen T, Lichtenstein AH, McGill HC, Pearson TA, Prewitt TE, Stone NJ, Horn LV, Weinberg R

A prospective study of triglyceride level, low-density lipoprotein particle diameter, and risk of myocardial infarction.

JAMA

Stampfer MJ, Krauss RM, Ma J, Blanche PJ, Holl LG, Sacks FM, Hennekens CH

Preventing heart attack and death in patients with coronary disease. Endorsed by the board of trustees of the American College of Cardiology.

Cardio-vascular nursing

Smith SC, Blair SN, Criqui MH, Fletcher GF, Fuster V, Gersh BJ, Gotto AM, Gould KL, Greenland P, Grundy SM, Hill MN, Hlatky MA, Houston-Miller N, Krauss RM, LaRosa J, Ockene IS, Oparil S, Pearson TA, Rapaport E, Starke RD

Differences in receptor binding of LDL subfractions.

Arteriosclerosis, thrombosis, and vascular biology

Campos H, Arnold KS, Balestra ME, Innerarity TL, Krauss RM

Hormone replacement therapy, hormone levels, and lipoprotein cholesterol concentrations in elderly women.

American journal of obstetrics and gynecology

Paganini-Hill A, Dworsky R, Krauss RM

Multilocus genetic determinants of LDL particle size in coronary artery disease families.

American journal of human genetics

Rotter JI, Bu X, Cantor RM, Warden CH, Brown J, Gray RJ, Blanche PJ, Krauss RM, Lusis AJ

Soy protein and serum lipids.

The New England journal of medicine

Krauss RM, Chait A, Stone NJ

Differing alpha-tocopherol oxidative lability and ascorbic acid sparing effects in buoyant and dense LDL.

Arteriosclerosis, thrombosis, and vascular biology

Tribble DL, Thiel PM, van den Berg JJ, Krauss RM

Overexpression of human apolipoprotein B-100 in transgenic rabbits results in increased levels of LDL and decreased levels of HDL.

Arteriosclerosis, thrombosis, and vascular biology

Fan J, McCormick SP, Krauss RM, Taylor S, Quan R, Taylor JM, Young SG

Low-density-lipoprotein subclasses and response to a low-fat diet in healthy men.

The American journal of clinical nutrition

Krauss RM, Dreon DM

Predominance of large LDL and reduced HDL2 cholesterol in normolipidemic men with coronary artery disease.

Arteriosclerosis, thrombosis, and vascular biology

Campos H, Roederer GO, Lussier-Cacan S, Davignon J, Krauss RM

Solvent drag of LDL across mammalian endothelial barriers with increased permeability.

The American journal of physiology

Rutledge JC, Curry FE, Blanche P, Krauss RM

LDL physical and chemical properties in familial combined hyperlipidemia.

Arteriosclerosis, thrombosis, and vascular biology

Hokanson JE, Krauss RM, Albers JJ, Austin MA, Brunzell JD

Persistence of low HDL-C levels after weight reduction in older men with small LDL particles.

Arteriosclerosis, thrombosis, and vascular biology

Katzel LI, Coon PJ, Rogus E, Krauss RM, Goldberg AP

Physical maps of human alpha (1,3)fucosyltransferase genes FUT3-FUT6 on chromosomes 19p13.3 and 11q21.

Genomics

McCurley RS, Recinos A, Olsen AS, Gingrich JC, Szczepaniak D, Cameron HS, Krauss R, Weston BW

Dense low density lipoproteins and coronary artery disease.

The American journal of cardiology

Krauss RM

LDL density and atherosclerosis.

JAMA

Austin MA, Krauss RM

Apolipoprotein E isoform phenotype and LDL subclass response to a reduced-fat diet.

Arteriosclerosis, thrombosis, and vascular biology

Dreon DM, Fernstrom HA, Miller B, Krauss RM

Differential expression of ARIA isoforms in the rat brain.

Neuron

Corfas G, Rosen KM, Aratake H, Krauss R, Fischbach GD

Multivariate analysis of the insulin resistance syndrome in women.

Arteriosclerosis and thrombosis : a journal of vascular biology

Edwards KL, Austin MA, Newman B, Mayer E, Krauss RM, Selby JV

Genetic predictors of FCHL in four large pedigrees. Influence of ApoB level major locus predicted genotype and LDL subclass phenotype.

Arteriosclerosis and thrombosis : a journal of vascular biology

Jarvik GP, Brunzell JD, Austin MA, Krauss RM, Motulsky AG, Wijsman E

Variations in high-density lipoprotein subclasses during the menstrual cycle.

Metabolism: clinical and experimental

Williams PT, Austin MA, Krauss RM

Cardiovascular disease and hyperlipidaemia.

Current opinion in lipidology

Krauss RM, Kesäniemi YA

Isolation of allele-specific, receptor-binding-defective low density lipoproteins from familial defective apolipoprotein B-100 subjects.

Journal of lipid research

Arnold KS, Balestra ME, Krauss RM, Curtiss LK, Young SG, Innerarity TL

Relations of plasma TG and HDL-C concentrations to body composition and plasma insulin levels are altered in men with small LDL particles.

Arteriosclerosis and thrombosis : a journal of vascular biology

Katzel LI, Krauss RM, Goldberg AP

Effects of low-fat diet, calorie restriction, and running on lipoprotein subfraction concentrations in moderately overweight men.

Metabolism: clinical and experimental

Williams PT, Krauss RM, Stefanick ML, Vranizan KM, Wood PD

Modification of LCAT activity and HDL structure. New links between cigarette smoke and coronary heart disease risk.

Arteriosclerosis and thrombosis : a journal of vascular biology

McCall MR, van den Berg JJ, Kuypers FA, Tribble DL, Krauss RM, Knoff LJ, Forte TM

Oxidative susceptibility of low density lipoprotein subfractions is related to their ubiquinol-10 and alpha-tocopherol content.

Proceedings of the National Academy of Sciences of the United States of America

Tribble DL, van den Berg JJ, Motchnik PA, Ames BN, Lewis DM, Chait A, Krauss RM

Low-density lipoprotein subclass patterns and lipoprotein response to a reduced-fat diet in men.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Dreon DM, Fernstrom HA, Miller B, Krauss RM

Associations of age, adiposity, alcohol intake, menstrual status, and estrogen therapy with high-density lipoprotein subclasses.

Arteriosclerosis and thrombosis : a journal of vascular biology

Williams PT, Vranizan KM, Austin MA, Krauss RM

Differential effects of estrogen on low-density lipoprotein subclasses in healthy postmenopausal women.

Metabolism: clinical and experimental

Campos H, Sacks FM, Walsh BW, Schiff I, O'Hanesian MA, Krauss RM

LDL subclass phenotypes and the insulin resistance syndrome in women.

Circulation

Selby JV, Austin MA, Newman B, Zhang D, Quesenberry CP, Mayer EJ, Krauss RM

Insulin resistance and hyperinsulinemia in individuals with small, dense low density lipoprotein particles.

The Journal of clinical investigation

Reaven GM, Chen YD, Jeppesen J, Maheux P, Krauss RM

The hypertriglyceridemia of acquired immunodeficiency syndrome is associated with an increased prevalence of low density lipoprotein subclass pattern B.

The Journal of clinical endocrinology and metabolism

Feingold KR, Krauss RM, Pang M, Doerrler W, Jensen P, Grunfeld C

Genetics of LDL subclass phenotypes in women twins. Concordance, heritability, and commingling analysis.

Arteriosclerosis and thrombosis : a journal of vascular biology

Austin MA, Newman B, Selby JV, Edwards K, Mayer EJ, Krauss RM

HDL and coronary artery disease.

Advances in internal medicine

Tribble DL, Krauss RM

Lipoprotein subclasses in genetic studies: the Berkeley data set.

Genetic epidemiology

Krauss RM, Williams PT, Blanche PJ, Cavanaugh A, Holl LG, Austin MA

Familial correlations of HDL subclasses based on gradient gel electrophoresis.

Arteriosclerosis and thrombosis : a journal of vascular biology

Williams PT, Vranizan KM, Austin MA, Krauss RM

LDL subclass phenotypes and triglyceride metabolism in non-insulin-dependent diabetes.

Arteriosclerosis and thrombosis : a journal of vascular biology

Feingold KR, Grunfeld C, Pang M, Doerrler W, Krauss RM

Production of polyacrylamide gradient gels for the electrophoretic resolution of lipoproteins.

Journal of lipid research

Rainwater DL, Andres DW, Ford AL, Lowe F, Blanche PJ, Krauss RM

Epidermal growth factor receptor in synaptic fractions of the rat central nervous system.

The Journal of biological chemistry

Faúndez V, Krauss R, Holuigue L, Garrido J, González A

Lipoprotein(a) in women twins: heritability and relationship to apolipoprotein(a) phenotypes.

American journal of human genetics

Austin MA, Sandholzer C, Selby JV, Newman B, Krauss RM, Utermann G

The metabolic impact of oral contraceptives.

American journal of obstetrics and gynecology

Krauss RM, Burkman RT

Reduced HDL2 cholesterol subspecies and elevated postheparin hepatic lipase activity in older men with abdominal obesity and asymptomatic myocardial ischemia.

Arteriosclerosis and thrombosis : a journal of vascular biology

Katzel LI, Coon PJ, Busby MJ, Gottlieb SO, Krauss RM, Goldberg AP

Correlations of plasma lipoproteins with LDL subfractions by particle size in men and women.

Journal of lipid research

Williams PT, Vranizan KM, Krauss RM

Associations of lipoproteins and apolipoproteins with gradient gel electrophoresis estimates of high density lipoprotein subfractions in men and women.

Arteriosclerosis and thrombosis : a journal of vascular biology

Williams PT, Krauss RM, Vranizan KM, Stefanick ML, Wood PD, Lindgren FT

Linkage of atherogenic lipoprotein phenotype to the low density lipoprotein receptor locus on the short arm of chromosome 19.

Proceedings of the National Academy of Sciences of the United States of America

Nishina PM, Johnson JP, Naggert JK, Krauss RM

Bimodality of plasma apolipoprotein B levels in familial combined hyperlipidemia.

Atherosclerosis

Austin MA, Horowitz H, Wijsman E, Krauss RM, Brunzell J

Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI.

Nature

Rubin EM, Krauss RM, Spangler EA, Verstuyft JG, Clift SM

Size transformations of intermediate and low density lipoproteins induced by unesterified fatty acids.

Journal of lipid research

Musliner TA, Long MD, Forte TM, Krauss RM

The tangled web of coronary risk factors.

The American journal of medicine

Krauss RM

Linkage analysis of low-density lipoprotein subclass phenotypes and the apolipoprotein B gene.

Genetic epidemiology

LaBelle M, Austin MA, Rubin E, Krauss RM

Increased immunoreactivity of apolipoprotein B epitopes during prolonged storage of low density lipoproteins.

Clinica chimica acta; international journal of clinical chemistry

La Belle M, Mok KS, Karu AE, Krauss RM

Familial defective apolipoprotein B-100: a mutation of apolipoprotein B that causes hypercholesterolemia.

Journal of lipid research

Innerarity TL, Mahley RW, Weisgraber KH, Bersot TP, Krauss RM, Vega GL, Grundy SM, Friedl W, Davignon J, McCarthy BJ

Inheritance of low density lipoprotein subclass patterns in familial combined hyperlipidemia.

Arteriosclerosis (Dallas, Tex.)

Austin MA, Brunzell JD, Fitch WL, Krauss RM

Identifying the predominant peak diameter of high-density and low-density lipoproteins by electrophoresis.

Journal of lipid research

Williams PT, Krauss RM, Nichols AV, Vranizan KM, Wood PD

The effects of polyunsaturated fat vs monounsaturated fat on plasma lipoproteins.

JAMA

Dreon DM, Vranizan KM, Krauss RM, Austin MA, Wood PD

Effects of exercise-induced weight loss on low density lipoprotein subfractions in healthy men.

Arteriosclerosis (Dallas, Tex.)

Williams PT, Krauss RM, Vranizan KM, Albers JJ, Terry RB, Wood PD

Lipoproteins and coronary heart disease.

Postgraduate medicine

Krauss RM

Regional adiposity patterns in relation to lipids, lipoprotein cholesterol, and lipoprotein subfraction mass in men.

The Journal of clinical endocrinology and metabolism

Terry RB, Wood PD, Haskell WL, Stefanick ML, Krauss RM

Familial defective apolipoprotein B-100: enhanced binding of monoclonal antibody MB47 to abnormal low density lipoproteins.

Proceedings of the National Academy of Sciences of the United States of America

Weisgraber KH, Innerarity TL, Newhouse YM, Young SG, Arnold KS, Krauss RM, Vega GL, Grundy SM, Mahley RW

Inheritance of low-density lipoprotein subclass patterns: results of complex segregation analysis.

American journal of human genetics

Austin MA, King MC, Vranizan KM, Newman B, Krauss RM

Low-density lipoprotein subclass patterns and risk of myocardial infarction.

JAMA

Austin MA, Breslow JL, Hennekens CH, Buring JE, Willett WC, Krauss RM

Effects of estrogen dose and smoking on lipid and lipoprotein levels in postmenopausal women.

American journal of obstetrics and gynecology

Krauss RM, Perlman JA, Ray R, Petitti D

Defective catabolism and abnormal composition of low-density lipoproteins from mutant pigs with hypercholesterolemia.

Biochemistry

Checovich WJ, Fitch WL, Krauss RM, Smith MP, Rapacz J, Smith CL, Attie AD

Coordinate changes in levels of human serum low and high density lipoprotein subclasses in healthy men.

Arteriosclerosis (Dallas, Tex.)

Krauss RM, Williams PT, Lindgren FT, Wood PD

Lipoprotein metabolism during acute inhibition of lipoprotein lipase in the cynomolgus monkey.

The Journal of clinical investigation

Goldberg IJ, Le NA, Ginsberg HN, Krauss RM, Lindgren FT

Lipoprotein subspecies and risk of coronary disease.

Clinical chemistry

Musliner TA, Krauss RM

The effects of oral contraceptives on plasma lipids and lipoproteins.

International journal of fertility

Krauss RM

Familial defective apolipoprotein B-100: low density lipoproteins with abnormal receptor binding.

Proceedings of the National Academy of Sciences of the United States of America

Innerarity TL, Weisgraber KH, Arnold KS, Mahley RW, Krauss RM, Vega GL, Grundy SM

Intermediate-density lipoproteins and progression of coronary artery disease in hypercholesterolaemic men.

Lancet (London, England)

Krauss RM, Lindgren FT, Williams PT, Kelsey SF, Brensike J, Vranizan K, Detre KM, Levy RI

Lipolysis products promote the formation of complexes of very-low-density and low-density lipoproteins.

Biochimica et biophysica acta

Musliner TA, McVicker KM, Iosefa JF, Krauss RM

Relationships of plasma estradiol, testosterone, and sex hormone-binding globulin with lipoproteins, apolipoproteins, and high density lipoprotein subfractions in men.

The Journal of clinical endocrinology and metabolism

Stefanick ML, Williams PT, Krauss RM, Terry RB, Vranizan KM, Wood PD

Relationship of dietary fat, protein, cholesterol, and fiber intake to atherogenic lipoproteins in men.

The American journal of clinical nutrition

Williams PT, Krauss RM, Kindel-Joyce S, Dreon DM, Vranizan KM, Wood PD

Genetic control of low-density-lipoprotein subclasses.

Lancet (London, England)

Austin MA, Krauss RM

Effects of oral contraceptives on lipid metabolism.

The Journal of reproductive medicine

Krauss RM

Lipoprotein subfractions of runners and sedentary men.

Metabolism: clinical and experimental

Williams PT, Krauss RM, Wood PD, Lindgren FT, Giotas C, Vranizan KM

Metabolic interrelationships of HDL subclasses.

Advances in experimental medicine and biology

Krauss RM, Nichols AV

Nondenaturing polyacrylamide gradient gel electrophoresis.

Methods in enzymology

Nichols AV, Krauss RM, Musliner TA

Presence of multiple subpopulations of lipoproteins of intermediate density in normal subjects.

Arteriosclerosis (Dallas, Tex.)

Musliner TA, Giotas C, Krauss RM

Single vertical spin density gradient ultracentrifugation.

Methods in enzymology

Chung BH, Segrest JP, Ray MJ, Brunzell JD, Hokanson JE, Krauss RM, Beaudrie K, Cone JT

Associations of diet and alcohol intake with high-density lipoprotein subclasses.

Metabolism: clinical and experimental

Williams PT, Krauss RM, Wood PD, Albers JJ, Dreon D, Ellsworth N

Modulation of apolipoprotein B antigenic determinants in human low density lipoprotein subclasses.

The Journal of biological chemistry

Teng B, Sniderman A, Krauss RM, Kwiterovich PO, Milne RW, Marcel YL

Associations of resting heart rate with concentrations of lipoprotein subfractions in sedentary men.

Circulation

Williams PT, Haskell WL, Vranizan KM, Blair SN, Krauss RM, Superko HR, Albers JJ, Frey-Hewitt B, Wood PD

The effect of cessation and resumption of moderate alcohol intake on serum high-density-lipoprotein subfractions. A controlled study.

The New England journal of medicine

Haskell WL, Camargo C, Williams PT, Vranizan KM, Krauss RM, Lindgren FT, Wood PD

Composition and distribution of low density lipoprotein fractions in hyperapobetalipoproteinemia, normolipidemia, and familial hypercholesterolemia.

Proceedings of the National Academy of Sciences of the United States of America

Teng B, Thompson GR, Sniderman AD, Forte TM, Krauss RM, Kwiterovich PO

Apolipoprotein and size heterogeneity in human umbilical cord blood low density lipoproteins.

Biochimica et biophysica acta

Davis PA, Forte TM, Kane JP, Hardman DA, Krauss RM, Blum CB

Does weight loss cause the exercise-induced increase in plasma high density lipoproteins?

Atherosclerosis

Williams PT, Wood PD, Krauss RM, Haskell WL, Vranizan KM, Blair SN, Terry R, Farquhar JW

Effects of two low-dose oral contraceptives on serum lipids and lipoproteins: differential changes in high-density lipoprotein subclasses.

American journal of obstetrics and gynecology

Krauss RM, Roy S, Mishell DR, Casagrande J, Pike MC

Increased exercise level and plasma lipoprotein concentrations: a one-year, randomized, controlled study in sedentary, middle-aged men.

Metabolism: clinical and experimental

Wood PD, Haskell WL, Blair SN, Williams PT, Krauss RM, Lindgren FT, Albers JJ, Ho PH, Farquhar JW

Effects of progestational agents on serum lipids and lipoproteins.

The Journal of reproductive medicine

Krauss RM

Regulation of high density lipoprotein levels.

The Medical clinics of North America

Krauss RM

Heterogeneity of serum low density lipoproteins in normal human subjects.

Journal of lipid research

Shen MM, Krauss RM, Lindgren FT, Forte TM

Intercorrelations among plasma high density lipoprotein, obesity and triglycerides in a normal population.

Lipids

Albrink MJ, Krauss RM, Lindgrem FT, von der Groeben J, Pan S, Wood PD

Interrelationships among subgroups of serum lipoproteins in normal human subjects.

Clinica chimica acta; international journal of clinical chemistry

Krauss RM, Lindgren FT, Ray RM

Changes in plasma lipoprotein distribution and formation of two unusual particles after heparin-induced lipolysis in hypertriglyceridemic subjects.

Proceedings of the National Academy of Sciences of the United States of America

Forte TM, Krauss RM, Lindgren FT, Nichols AV

Effects of estrogens and progestins on high density lipoproteins.

Lipids

Krauss RM, Lindgren FT, Wingerd J, Bradley DD, Ramcharan S

Serum high-density-lipoprotein cholesterol in women using oral contraceptives, estrogens and progestins.

The New England journal of medicine

Bradley DD, Wingerd J, Petitti DB, Krauss RM, Ramcharan S

Effect of pesticides on testicular function.

Urology

Marshall S, Whorton D, Krauss RM, Palmer WS

Infertility in male pesticide workers.

Lancet (London, England)

Whorton D, Krauss RM, Marshall S, Milby TH

Changes in serum high density lipoproteins in women on oral contraceptive drugs.

Clinica chimica acta; international journal of clinical chemistry

Krauss RM, Lindgren FT, Silvers A, Jutagir R, Bradley DD

Subclinical chronic pancreatitis in type I hyperlipoproteinemia.

The American journal of medicine

Krauss RM, Levy AG

Therapeutic failure in familial type II hyperlipoproteinemia.

Metabolism: clinical and experimental

Witters LA, Herbert PN, Shulman RS, Krauss RM, Levy RI

Positional specificity of triglyceride lipases in post-heparin plasma.

The Journal of biological chemistry

Assmann G, Krauss RM, Fredrickson DS, Levy RI

Further observations on the activation and inhibition of lipoprotein lipase by apolipoproteins.

Circulation research

Krauss RM, Herbert PN, Levy RI, Fredrickson DS

Selective measurement of two different triglyceride lipase activities in rat postheparin plasma.

Journal of lipid research

Krauss RM, Windmueller HG, Levy RI, Fredrickson DS

A biochemical and morphologic study of very low density lipoproteins in carbohydrate-induced hypertriglyceridemia.

The Journal of clinical investigation

Ruderman NB, Jones AL, Krauss RM, Shafrir E